17591-59-2Relevant academic research and scientific papers
Microwave-assisted synthesis of 3,5-Dibenzyl-4-amino-1,2,4-triazole and its diazo ligand, metal complexes along with anticancer activity
Jha, Anjali,Murthy,Durga,Sundari
experimental part, p. 1571 - 1577 (2011/12/22)
Synthesis of 3,5-dibenzyl-4-amino-1,2,4-triazole was accomplished via a conventional method as well as microwave irradiation method, followed by diazotization and coupling with 2,4-pentanedione. The dinucleating ligand was isolated and complexed with Ni(II), Cu(II) and Ru(III) chlorides. These complexes were screened on Jurkat, Raji & PBMC cell lines for anticancer activity. Ruthenium complexes showed potential anticancer activities.
Process for the synthesis of 4-amino-1,2,4-(4h)triazole derivatives
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, (2008/06/13)
A process for preparing a 4-amino-1,2,4-(4H)triazole derivative compositions having the formula STR1 wherein R is hydrogen or an alkyl group containing from 1 to about 10 carbon atoms, which alkyl group can be additionally substituted by one or more aryl, heteroaryl, hydroxy, or alkenyl substituents, comprising the step of reacting hydrazine or an aqueous hydrazine solution with a carboxylic acid having the formula RCO2 H in the presence of an insoluble polymer containing acidic functional groups sufficiently strong to cause the reaction to proceed under mild conditions to produce a product of high yield and purity.
