175913-32-3

Basic information

• Product Name: 1H-Indole, 7-Methoxy-4-nitro-
• Synonyms: 1H-Indole, 7-Methoxy-4-nitro-;7-Methoxy-4-nitro-1H-indole
• CAS NO: 175913-32-3
• Molecular Formula: C9H8N2O3
• Molecular Weight: 192.17142
• Mol File: 175913-32-3.mol

Chemical Properties

• Boiling Point: 420.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.395±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.25±0.30(Predicted)
• CAS DataBase Reference: 1H-Indole, 7-Methoxy-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 7-Methoxy-4-nitro-(175913-32-3)
• EPA Substance Registry System: 1H-Indole, 7-Methoxy-4-nitro-(175913-32-3)

Safety Data

• Hazardous Substances Data: 175913-32-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Indole, 7-methoxy-4-nitrois used as a building block in the synthesis of various biologically active molecules. Its unique structure and reactivity contribute to the development of drugs with potential therapeutic applications.
Used in Organic Synthesis:
1H-Indole, 7-methoxy-4-nitroserves as an important intermediate in organic synthesis, enabling the creation of a wide range of chemical compounds.
Used in Research and Development:
1H-Indole, 7-methoxy-4-nitrohas potential applications in research and development for the discovery of new therapeutic agents, thanks to its distinctive properties and reactivity.
Used in Agrochemicals Production:
1H-Indole, 7-methoxy-4-nitrois also utilized in the production of agrochemicals, where its unique structure aids in the development of effective and targeted products for agricultural applications.
Used in Fine Chemicals Production:
1H-Indole, 7-methoxy-4-nitro-'s versatility and reactivity make it a valuable intermediate in the production of fine chemicals, contributing to the creation of high-quality specialty products.

Upstream product

• 3189-22-8 7-methoxy-1H-indole 
• 146073-32-7 7-(methyloxy)-1-(phenylsulfonyl)-1H-indole 
• 959687-53-7 1-benzenesulfonyl-7-methoxy-4-nitro-1H-indole 

Relevant articles and documents

Method for treating proliferative disorders associated with mutations in c-Met

The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating c-Met associated cancers, in a subject in need thereof.

METHOD FOR INHIBITING TOPOISOMERASE II

The present invention relates to compounds that inhibit the activity of Hsp90 and inhibit topoisomerase II.

Method for treating proliferative disorders associated with protooncogene products

The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating Bcr-Abl, FLT-3, EGFR, c-Kit, B-raf, and NPM-ALK associated cancers, in a subject in need thereof.

TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of treating or inhibiting angiogenesis in a subject in need thereof and methods for blocki

METHOD FOR TREATING INFLAMMATORY DISORDERS

The present invention relates to a method for suppressing the immune system in a subject in need thereof, and a method for treating an inflammatory or immune disorder in a subject in need thereof.

METHOD FOR TREATING INFECTIONS

The present invention relates to compounds that inhibit the activity of Hsp90 and methods of using these compounds for treating or preventing infection.

METHOD FOR TREATING NON-HODGKIN'S LYMPHOMA

The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating non-Hodgkin's lymphoma, in a subject in need thereof.

TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventin

Efficient mononitration of indolic compounds with nitric acid impregnated on silica gel

The methoxyindoles (N-benzenesulfonyl and 2-carbomethoxy) were mononitrated with nitric acid adsorbed on silica gel under mild conditions to give mononitroindoles in good chemical yields.