176-80-7 Usage
General Description
1-Azaspiro[4.5]decane, also known as SPD (spiro[4.5]decane) or BMS-204352, is a chemical compound that belongs to the class of spiro compounds. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs, including antipsychotics and antidepressants. SPD has a unique spirocyclic structure that makes it a valuable intermediate for the production of bioactive compounds. It has also been studied for its potential applications in materials science, including as a component in liquid crystals and as a ligand in metal complex catalysts. Additionally, SPD has been investigated for its potential role as a chiral auxiliary in asymmetric synthesis, making it a versatile and important chemical in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 176-80-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,7 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 176-80:
(5*1)+(4*7)+(3*6)+(2*8)+(1*0)=67
67 % 10 = 7
So 176-80-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H17N/c1-2-5-9(6-3-1)7-4-8-10-9/h10H,1-8H2
176-80-7Relevant articles and documents
Straightforward and effective synthesis of γ-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes
Ma, Xiaofeng,Lubin, Hodney,Ioja, Eniko,Kékesi, Orsolya,Simon, ágnes,Apáti, ágota,Orbán, Tamás I.,Héja, László,Kardos, Julianna,Markó, István E.
, p. 417 - 423 (2016)
Supply of major metabolites such as γ-aminobutyric acid (GABA), β-alanine and taurine is an essential instrument that shapes signalling, proper cell functioning and survival in the brain and peripheral organs. This background motivates the synthesis of no
SYNTHESIS AND REACTIONS OF 1-AZASPIROCYCLES: 1-AZASPIRODECANE AND 1-AZASPIRONONANE RING SYSTEMS.
Bryce, Martin R.,Gardiner, John M.,Horton, Paul J.,Smith, Susan A.
, p. 116 - 124 (2007/10/02)
Nitrocyclohexane reacted with methyl acrylate in the presence of Triton-B to yield nitro-ester (4) which cyclised to spirolactam (5) on treatment with zinc in ethanolic hydrochloric acid.Lactam (5) was reduced to pyrrolidine (7) by lithium aluminium hydri
