176038-86-1Relevant academic research and scientific papers
An expeditious click approach towards the synthesis of galactose coated novel glyco-dendrimers and dentromers utilizing a double stage convergent method
Agrahari, Anand K.,Mukherjee, Rishav,Singh., Anoop S.,Tiwari, Vinod K.
, p. 31553 - 31562 (2020/09/21)
The primary motive behind this article is to bring to the forefront a unique kind of dendrimer which has remained a dark horse since its discovery, namely dentromer. We herein report the synthesis of glycodendrimers and glycodentromers crowned with galactose units by harnessing an expeditious synthesis of dendrimer core 18 and dentromer core 19, divergently with branching directionality (1 → 2) and (1 → 3), respectively. A competent, double stage convergent synthetic path was chosen to facilitate ease of refining and spectroscopic elucidations. By exploiting a Cu(i)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction strategy, we successfully developed a new series of galactosylated dendrimers 20, 21, 22, and 24 containing 6, 12, 18, and 18 peripheral galactose units, respectively. We are first to report the practical synthesis of 9-peripheral galactose coated glycodentromer 23 (0th generation) and 27-peripheral galactose coated glycodentromer 25 (1st generation). These synthesized scaffolds were characterized by spectral studies such as 1H, 13C NMR, FT-IR, MALDI-TOF MS, HRMS and SEC analysis. Additionally, gel permeation chromatography depicted the regular progression in size from 6 to 27-peripheral galactose coated glycodendrimers along with glycodentromers, with their high monodispersity. Also, the glyco-dendrimers and dentromers synthesized from two different hypercore units i.e. dendrimers core (18) and dentromer core (19), have been supported by their UV-visible absorbance and emission spectroscopy. This journal is
Enhanced electro-optic activity of two novel bichromophores which are synthesized by Cu(I) catalyzed click-reaction
He, Yanling,Chen, Lu,Liu, Fenggang,Zhang, Hua,Huo, Fuyang,Chen, Zhuo,Liu, Jialei,Zhen, Zhen,Liu, Xinhou,Bo, Shuhui
, p. 756 - 763 (2017/01/17)
Two novel bichromophores YL1 and YL2 based on traditional aniline chromophore YL were synthesized by Cu(I) catalyzed click-reaction and systematically investigated in this paper. The UV–Vis, electrochemical property, thermal stability and EO activity of t
π-Conjugated polymers with pendant coumarins: Design, synthesis, characterization, and interactions with carbon nanotubes
Imit, Mokhtar,Imin, Patigul,Adronov, Alex
, p. 759 - 768 (2016/10/12)
A series of new fluorene-based π-conjugated polymers having coumarin derivatives as part of dendritic side chains were designed and prepared using the Suzuki-Miyaura cross-coupling reaction. A new coumarin derivative bearing a heptyl side chain for solubility was utilized to ensure solubility of the final polymers. It was found that fluorescence resonance energy transfer (FRET) from the coumrains to the polyfluorene backbone was efficient, especially for the polymers decorated with lower-generation dendrons. Each of the polymers was found to interact strongly with the surface of single-walled carbon nanotubes (SWNTs) in THF, and their ability to selectively disperse specific SWNT chiralities was investigated. Photoluminescence studies revealed that the strong polymer emission is efficiently quenched in the corresponding supramolecular complexes with SWNTs. This high quenching efficiency indicates that the coumarin-polymer FRET system can be supramolecularly bound to the surface of (SWNTs to produce an energy transfer system in which the energy absorbed by the donor coumarin chromophores is channeled to the SWNTs.
Synthesis and characterization of novel dendritic compounds bearing a porphyrin core and cholic acid units using "click chemistry"
Aguilar-Ortíz, Edgar,Lévaray, Nicolas,Vonlanthen, Mireille,Morales-Espinoza, Eric G.,Rojas-Aguirre, Yareli,Zhu, Xiao Xia,Rivera, Ernesto
, p. 110 - 120 (2016/05/19)
Four novel dendritic molecules bearing a porphyrin core and peripheral cholic acid units (TPPh(Zn) Tetra-CA, TPPh(2H) Tetra-CA, TPPh(Zn) Octa-CA and TPPh(2H) Octa-CA) have been synthesized by the "click chemistry" approach, using azide-alkyne couplings. These compounds are fully characterized by 1H and 13C NMR spectroscopy and MALDI-TOF. The optical properties of the dendronized porphyrins are studied by absorption and fluorescence spectroscopy in different solvents, in order to study the amphiphilic properties of the cholic acid units in combination with the optical response of the porphyrin unit. After complexation with Zn, the metallated porphyrins (TPPh(Zn) tetra-CA and TPPh(Zn) octa-CA) tend to form J-aggregates in solvents of different polarity, whereas the free base porphyrins TPPh(2H) tetra-CA and TPPh(2H) octa-CA behaved differently. The aggregation phenomenon has been investigated by varying the polarity of the environment, temperature and metallation.
Effects of dendron generation and salt concentration on phase structures of dendritic-linear block copolymers with a semirigid dendron containing PEG tails
Cai, Huanhuan,Jiang, Guoliang,Shen, Zhihao,Fan, Xinghe
experimental part, p. 6176 - 6184 (2012/10/18)
We prepared a series of dendritic-linear block copolymers (DLBCPs) bearing a semirigid Percec-type dendron with ionophilic poly(ethylene glycol) (PEG) tails and a polystyrene (PS) linear polymer by nitroxide-mediated living radical polymerization (NMRP).
Dye-incorporated water-soluble polymer via click triazole formation
Jang, Byungkwon,Kim, Sung Yoon,Do, Jung Yun
experimental part, p. 217 - 223 (2012/05/05)
A click triazole-polymerization is proposed for the synthesis of a water-soluble polymer dye. 4,4′-Diazidostilbene-2,2′-disulfonate (DASS) sodium salt reacted with a diacetylenic derivative of para-methyl red (PMR) in water, which was catalyzed by copper
"Click" chemistry-mediated phenylene-cored carborane dendrimers
Dash, Barada Prasanna,Satapathy, Rashmirekha,Bode, Barrie P.,Reidl, Cory T.,Sawicki, James W.,Mason, Allen J.,Maguire, John A.,Hosmane, Narayan S.
experimental part, p. 2931 - 2935 (2012/06/15)
Phenylene-cored small dendrimers containing three to nine peripheral o-carborane clusters were synthesized via Cu(I)-catalyzed Huisgen-type azide alkyne cycloaddition reactions. The resulting dendrimers have been characterized by IR and NMR spectroscopy a
METHOD OF USING CLICK CHEMISTRY TO FUNCTIONALIZE DENDRIMERS
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Page/Page column 15, (2008/06/13)
A library of functionalized dendritic macromolecules was prepared in extremely high yields using no protecting group strategies and with only minimal purification steps through the use of copper(l)-catalyzed 1 ,3-dipolar cycloaddition of azides and termin
A chemoselective approach for the accelerated synthesis of well-defined dendritic architectures
Antoni, Per,Nystroem, Daniel,Hawker, Craig J.,Hult, Anders,Malkoch, Michael
, p. 2249 - 2251 (2007/12/27)
A chemoselective and layered growth approach has been developed for the synthesis of dendrimers, combining Click chemistry with traditional esterification/etherification reactions, without the need for activation steps and with excellent overall yields. T
Structurally diverse dendritic libraries: A highly efficient functionalization approach using click chemistry
Malkoch, Michael,Schleicher, Kristin,Drockenmuller, Eric,Hawker, Craig J.,Russell, Thomas P.,Wu, Peng,Fokin, Valery V.
, p. 3663 - 3678 (2008/02/01)
The high fidelity and efficiency of Click chemistry are exploited in the synthesis of a library of chain end functionalized dendritic macromolecules. In this example, the selectivity of the Cu-catalyzed [3 + 2π] cycloaddition reaction of azides with termi
