176041-72-8Relevant academic research and scientific papers
Mechanism-based inactivation of α-chymotrypsin
Ohba, Tsuyoshi,Tsuchiya, Naoki,Nishimura, Kuniko,Ikeda, Eitatsu,Wakayama, Jun,Takei, Hisashi
, p. 543 - 546 (2007/10/03)
The peptidyl ester derivatives of 2,2-dichlorocyclopropanol and the amide derivative of 2,2-dichlorocyclopropylamine were prepared as novel mechanism-based inactivators of α-chymotrypsin. The esters inactivated α-chymotrypsin irreversibly but the amide did not show any irreversible inhibitory activity toward α-chymotrypsin.
