27317-69-7

Basic information

• Product Name: BOC-ALA-ALA-OH
• Synonyms: BOC-ALA-ALA-OH;BOC-ALA-ALA-OH H2O;BOC-L-ALANYL-L-ALANINE H2O;BOC-L-ALANYL-L-ALANINE MONOHYDRATE;N-tert-Butoxycarbonyl-L-alanyl-L-alanine;Boc-Ala-Ala;Boc-AA-OH;Boc-L-Ala-L-Ala-OH
• CAS NO: 27317-69-7
• Molecular Formula: C₁₁H₂₀N₂O₅
• Molecular Weight: 260.29
• EINECS: 1533716-785-6
• Mol File: 27317-69-7.mol
• Article Data: 30

Chemical Properties

• Melting Point: 132-133 °C
• Boiling Point: 483.5°Cat760mmHg
• Flash Point: 246.2°C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 1.12E-10mmHg at 25°C
• Refractive Index: 1.478
• Storage Temp.: -15°C
• PKA: 3.52±0.10(Predicted)
• CAS DataBase Reference: BOC-ALA-ALA-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-ALA-ALA-OH(27317-69-7)
• EPA Substance Registry System: BOC-ALA-ALA-OH(27317-69-7)

Safety Data

• Hazardous Substances Data: 27317-69-7(Hazardous Substances Data)

Usage

General Description

BOC-ALA-ALA-OH is a chemical compound that consists of two alanine amino acids (ALA) connected by a BOC (tert-butyloxycarbonyl) group, with a hydroxyl group (OH) at the end. The BOC group serves as a protective group for the amino group of the alanine residues, preventing unwanted reactions during chemical synthesis. BOC-ALA-ALA-OH is commonly used in peptide synthesis as a building block for creating longer peptide chains. BOC-ALA-ALA-OH is stable and easy to handle, making it a valuable tool in the production of peptides for various research and industrial applications.

InChI:InChI=1/C11H20N2O5/c1-6(8(14)12-7(2)9(15)16)13-10(17)18-11(3,4)5/h6-7H,1-5H3,(H,12,14)(H,13,17)(H,15,16)

Upstream product

• 19794-10-6 (S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanoate 
• 18670-98-9 N-(tert-butoxycarbonyl)-L-alanyl-L-alanine benzyl ester 
• 56-41-7 L-alanin 
• 15761-38-3 L-N-Boc-Ala 
• 1115-59-9 (S)-alanine ethyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1146929-22-7 (S)-O-(tert-butyl) N-(thietan-2-on-3-yl) carbamate 
• 1464-43-3 seleno-L-cystine 
• 2483-49-0 tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester 
• 83904-90-9 Boc-Ala-N-hydroxysuccinimide ester 
• 73488-76-3 N-t-butyloxycarbonyl-alanine-N'-hydroxysuccinimide ester 
• 1280225-71-9 C₁₈H₂₈N₂O₆ 
• 1948-31-8 di-L-alanine 

Downstream Products

• 19794-10-6 (S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanoate 
• 130508-08-6 p-Nitrophenyl N-(t-Boc-L-alanyl-L-alanyl-L-prolylmethyl)-N-isopropyl carbamate 
• 1013398-85-0 9-[4'-N-(N-t-Boc-L-alanyl-L-alanyl)aminophenyl]acridine 
• 1261612-77-4 (1-{1-[(2-oxo-1,4-diphenyl-azetidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 18671-06-2 N-t-butoxycarbonyl-L-alanyl-L-alanyl-L-alanine benzyl ester 
• 1374840-05-7 C₂₆H₃₆N₄O₅ 
• 1374840-03-5 C₂₁H₃₃N₃O₅ 
• 883565-12-6 C₁₆H₂₈N₂O₆ 
• 885065-15-6 C₃₂H₄₁F₂N₅O₆S 
• 155518-27-7 N^α-tert-butoxycarbonyl-L-alanyl-L-alanyl-L-alanyl-(N^ε-benzyloxycarbonyl)-L-lysyl-L-alanyl-(N^ε-(benzo-18-crown-6)-4-carbonyl)-L-lysyl-L-alanine methyl ester 
• 530103-33-4 N-tBOC-L-Ala-L-Ala-D-Phe-1-anthraquinonylhydrazide 
• 270090-90-9 N-Boc-O-(4-hydroxyphenacyl)-Ala-Ala 
• 176041-72-8 (S)-2-[(S)-2-((S)-2-tert-Butoxycarbonylamino-propionylamino)-propionylamino]-3-phenyl-propionic acid 2,2-dichloro-cyclopropyl ester 

Relevant articles and documents

Synthesis of Peptidoglycan Fragments from Enterococcus faecalis with Fmoc-Strategy for Glycan Elongation

Peptidoglycan (PGN) is an essential structural component of the bacterial cell wall conferring cell shape, which can be recognized by host-recognition proteins and receptors as well as bacterial surface proteins. In this work, the PGN partial structures from Enterococcus faecalis that contain a tetrasaccharide and an octasaccharide with a unique heptapeptide were synthesized via an Fmoc-strategy for elongation of the glycan chains. Namely, a 4′-O-Fmoc-protected disaccharide was utilized as the key intermediate in this efficient synthetic pathway for preparing various PGN fragments. Both the tetrasaccharide and octasaccharide with the unique heptapeptide were successfully synthesized for the first time.

ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF

The invention provides anti-VISTA antibody drug conjugates which may be used for targeted delivery of anti-inflammatory agents such as steroids to immune cells, e.g., myeloid cells. The invention also provides methods of using anti-VISTA antibody drug conjugates in the treatment of inflammatory and/or autoimmune conditions and/or for alleviating the toxicity of anti-inflammatory agents such as steroids.

The effect of monosaccharides on self-assembly of benzenetricarboxamides

The interaction between monosaccharides exhibits an important role in the assembly of monosaccharide-containing molecules. In this work, three common monosaccharides, glucose, galactose and mannose, are employed to investigate the effect of monosaccharide on the self-assembly of benzenetricarboxamide (BTA) core-containing molecules. In the presence of monosaccharides, three benzenetricarboxamide derivatives aggregate into different ordered structures. When alanine linkers are introduced to these molecules between the core and the monosacchride, morphologies of three types of monosaccharide BTAs turned to disordered, meanwhile their structures become similar with the increase of the length of alanine linkers, indicating the disappearance of the monosaccharide effects.