17605-08-2Relevant academic research and scientific papers
The efficient synthesis of substituted 2-methylbenzofurans
Mikhalyonok, Sergei G.,Arol, Aliaxandr S.,Litvinau, Dmitri A.,Kuz’menok, Nina M.,Bezborodov, Vladimir S.
, p. 205 - 211 (2019/05/15)
[Figure not available: see fulltext.] The efficient synthesis of substituted 2-methylbenzofurans by aromatization of accessible allyl-substituted cyclohex-2-enones in the presence of iodine followed by dehydroiodination of the 2-iodomethyl-2,3-dihydrobenz
A concomitant allylic azide rearrangement/intramolecular azide-alkyne cycloaddition sequence
Vekariya, Rakesh H.,Liu, Ruzhang,Aube, Jeffrey
supporting information, p. 1844 - 1847 (2014/05/06)
An intramolecular Huisgen cycloaddition of an interconverting set of isomeric allylic azides with alkynes affords substituted triazoles in high yield. The stereoisomeric vinyl-substituted triazoloxazines formed depend on the rate of cycloaddition of the d
Tributyltin hydride-mediated synthesis of bicyclic carbocycles initiated by Et3B/O2
Prakash, Chandran,Rajeshwaran, Ganesan Gobi,Mohanakrishnan, Arasambattu K.
body text, p. 2097 - 2107 (2010/08/07)
Synthesis of bicyclic carbocycles involving tributyltin hydride-mediated-carbonyl radical cyclization reaction at room temperature has been reported. Copyright Taylor & Francis Group, LLC.
Synthesis of angularly fused carbocycles via tandem radical cyclization of α-carbonyl radicals
Prakash, Chandran,Mohanakrishnan, Arasambattu K.
experimental part, p. 1535 - 1543 (2009/04/11)
An α-carbonyl radical cyclization approach towards the synthesis of angularly fused tricyclic systems is described. On reduction with tributyltin hydride, bromo ketones yield a α-carbonyl radical that undergoes successive 5-exo-dig/trig cyclizations, resu
Stereoselective syntheses of (±)-komaroviquinone and (±)-faveline methyl ether through intramolecular Heck reaction
Sengupta, Sujaya,Drew, Michael G. B.,Mukhopadhyay, Ranjan,Achari, Basudeb,Banerjee, Asish Kr
, p. 7694 - 7700 (2007/10/03)
An efficient, flexible, and stereoselective convergent route for constructing the trans-10-hydroxy-1,1-dimethyloctahydrodibenzo[a,d]cyclohepten- 7-ones (5a-c) was achieved via intramolecular Heck reaction. This strategy has been successfully implemented for the syntheses of (±)-komaroviquinone (3) through (±)-coulterone dimethyl ether (5c) and (±)-faveline methyl ether (1a).
Sterically hindered lithium dialkylcuprates for the generation of highly functionalized mixed cuprates through a halogen-copper exchange
Piazza, Claudia,Knochel, Paul
, p. 3263 - 3265 (2007/10/03)
Even aldehyde and ketone functions are tolerated in mixed organocuprates prepared by copper-halogen exchange using (Me3CCH2)2CuLi (Neopent2CuLi) or (PhMe2CCH2)2CuLi (Neophyl2CuLi). The steric hindrance of the neopentyl and neophyl groups is essential to ensure the chemoselectivity of the reaction (see scheme), and therefore allows a general preparation of polyfunctionalized organocuprates.
A Stereocontrolled Synthesis and X-Ray Crystal Structure of a 2,3,3-Trisubstituted Cyclohexanone
Cairns, Peter M.,Howes, Colin,Jenkins, Paul R.,Russell, David R.,Sherry, Lesly
, p. 1487 - 1488 (2007/10/02)
A γ,δ-unsaturated amide, prepared by an amide acetal Claisen rearrangement, has been subjected to hydroxy-lactonisation, and reductive cleavage of the corresponding keto-lactone with aluminium amalgam has led to a trisubstituted cyclohexanone derivative w
3-Methylcyclohex-2-enone Derivatives as Initiators of Cyclisation. Part 1. Introduction and Synthesis of 2-Substituted 3-methylcyclohex-2-enones
Amupitan, Joseph A.,Huq, Enamul,Mellor, Michael,Scovell, Edward G.,Sutherland, James K.
, p. 747 - 749 (2007/10/02)
A series of C-2 substituted 3-methylcyclohex-2-enones has been prepared using the Hagemann ester route.A new synthesis of these compounds has been developed which involves the alkylation of the N,N-diethylaminoethyl ether of 1-hydroxy-5-methylcyclohexa-1,5-diene.The cyclohexenones have been converted into the corresponding α,β-epoxyketones using alkaline hydrogen peroxide.
Regiochemical Control in Intramolecular Photochemical Reactions of 1,5-Hexadien-3-ones and 1-Acyl-1,5-hexadienes
Wolff, Steven,Agosta, William C.
, p. 1292 - 1299 (2007/10/02)
Both 1,5-hexadien-3-ones (7) and 1-acyl-1,5-hexadienes (8) generally undergo intramolecular photochemical cyclization by way of 1,5 (crossed) closure (see 2), as do other derivatives of 1,5-hexadienes (1).Through study of the photochemistry of 14 members
