17607-01-1

Basic information

• Product Name: 1-nitroxanthone
• CAS NO: 17607-01-1
• Molecular Weight: 241.203
• Mol File: 17607-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-nitroxanthone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-nitroxanthone(17607-01-1)
• EPA Substance Registry System: 1-nitroxanthone(17607-01-1)

Safety Data

• Hazardous Substances Data: 17607-01-1(Hazardous Substances Data)

Upstream product

• 90-47-1 xanth-9-one 

Downstream Products

• 719-41-5 1-hydroxy-9H-xanthen-9-one 
• 71641-59-3 1-anilino-xanthen-9-one 
• 54829-44-6 1-amino-9H-xanthen-9-one 

Relevant articles and documents

Synthesis and biological evaluation of biphenyl amides that modulate the US28 receptor

To prepare and biologically evaluate 38 new potential US28 allosteric modulators, we employed a straightforward synthetic route involving radical arylation. The study was based on a former lead structure but with the dihydroisoquinolinone moiety replaced by substituted biphenyls. The investigation of structure-activity relationships among the new biphenyl-derived ligands led to a preliminary pharmacophore model and the discovery of four promising candidates with full inverse agonist properties. Hit HCMV GPCRs ASAP! Employing a straightforward synthetic access involving radical arylation, 38 new potential US28 allosteric modulators were prepared and biologically evaluated. The investigation of structure-activity relationships among the new biphenyl-derived ligands led to a consistent model and the discovery of four promising candidates with full inverse agonist properties. Copyright