176106-08-4Relevant articles and documents
Green synthesis and antibacterial, antifungal activities of 4H-pyran, tetrahydro-4H-chromenes and spiro2-oxindole derivatives by highly efficient Fe3O4@SiO2@NH2@Pd(OCOCH3)2 nanocatalyst
Aghamohammadi, Parinaz,Poor Heravi, Mohammad Reza,Vessally, Esmail
, (2021/10/12)
An efficiently, magnetically retrievable Fe3O4@SiO2@NH2@Pd(OCOCH3)2 nanoparticles was successfully synthesized and affirmed by several physicochemical characterization tools, such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-disoersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FT-IR), and power X-ray diffraction. Thereafter, the catalytic performance of this environmentally benign nanocatalyst was investigated in the one-pot multicomponent synthesis of biologically important 2-amino-3-cyano-4H-pyran, tetrahydro-4H-chromenes and spiro2-oxindole derivatives. The reaction was simply achieved via one-pot three-component reaction of arylaldehydes, malononitrile and dimedone/isatins/methylaceto acetate ethanol at room temperature, with excellent yields and high purity. A new catalytic system, recyclability of reaction medium, little reaction times and excellent yields with easy workup render this protocol more attractive and economically viable.
Synthesis and antibacterial study of 2-amino-4H-pyrans and pyrans annulated heterocycles catalyzed by sulfated polysaccharide-coated BaFe12O19 nanoparticles
Amirnejat, Sara,Nosrati, Aliakbar,Peymanfar, Reza,Javanshir, Shahrazad
, p. 3683 - 3701 (2020/05/13)
Abstract: In this procedure, the synthesis of ecofriendly, magnetically retrievable BaFe12O19 was reported using a sulfated polysaccharide of?algal origin, Irish moss (IM), as bio-matrix and capping agent. The characterization of BaFe12O19@IM was performed by some physicochemical characterization tools, such?as Fourier transform?infrared spectroscopy, X-ray powder diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, vibrating sample magnetometer, and thermogravimetric analysis. The catalytic performance and recyclability of the introduced heterogeneous catalyst have been explored in the one-pot synthesis of 2-amino-4H-pyrans and pyrans annulated heterocyclic compounds via a three-component reaction between aldehydes, malononitrile, and various C–H activated acidic compound under green reaction conditions. This environmentally benign catalyst displayed high catalytic activity and effective reusability and could maintain its high catalytic efficiency even after six recycling runs. Furthermore, the antibacterial activity of BaFe12O19@IM and the selected compound (4a) toward two types of clinically isolated bacterial strains Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) was evaluated. The results revealed that BaFe12O19@IM and 2-amino-4-(4-chlorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (4a) showed an effective antibacterial activity against gram-positive S. aureus. Graphic abstract: [Figure not available: see fulltext.].
Facile: In situ synthesis and characterization of a novel PANI/Fe3O4/Ag nanocomposite and investigation of catalytic applications
Maleki, Ali,Movahed, Hamed,Ravaghi, Parisa,Kari, Tooraj
, p. 98777 - 98787 (2016/11/02)
A novel magnetic polyaniline (PANI)/Fe3O4/Ag nanocomposite was successfully synthesized via in situ polymerization induced by ultraviolet irradiation (λ = 254 nm) in the presence of Fe3O4 nanoparticles and Ag cations as oxidants. The morphology and structure of the newly prepared nanocomposite was characterized by Fourier-transform infrared spectrometry, X-ray diffraction, energy-dispersive X-ray spectrometry, vibrating sample magnetometry, transmission electron microscopy, field-emission scanning electron microscopy and inductively coupled plasma optical emission spectrometry. The corresponding saturation magnetization for the nanocomposite was about 20.37 emu g-1. The catalytic properties of the nanocomposite were evaluated in the synthesis of biologically and pharmaceutically important pyran derivatives and it was shown to produce high yields, short reaction times and an easy work-up process. The superparamagnetic properties of the nanocatalyst allowed easy separation from the reaction media.
