176216-57-2

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 171369-22-5 1-Benzyloxy-3,5-bis-[3-(4-tert-butyl-phenoxy)-propoxy]-benzene 
• 98-54-4 para-tert-butylphenol 
• 59434-20-7 1,3,5-tri-O-benzylphloroglucinol 
• 216968-15-9 3-{3,5-bis-[3-(4-tert-butyl-phenoxy)-propoxy]-phenoxy}-propan-1-ol 
• 109-64-8 1,3-dibromo-propane 
• 171369-23-6 3,5-Bis-[3-(4-tert-butyl-phenoxy)-propoxy]-phenol 
• 216968-14-8 3-[3,5-bis(benzyloxy)phenoxy]propanol 
• 216968-13-7 5-(3-hydroxypropyloxy)-1,3-resorcinol 
• 3245-63-4 1-bromo-3-(4'-tert-butylphenyloxy)propane 
• 63604-98-8 1,3-dibenzylphloroglucinol 

Downstream Products

• 176216-56-1 C₇₉H₁₀₃BrO₁₃ 
• 216968-18-2 3-[3,5-bis-(3-{3,5-bis-[3-(4-tert-butyl-phenoxy)-propoxy]-phenoxy}-propoxy)-phenoxy]-propan-1-ol 

Relevant academic research and scientific papers

An accelerated, improved synthetic route for the preparation of polyether-based dendritic fragments

An accelerated, improved synthetic strategy for the rapid construction of two different series of polyether-based dendritic fragments is described. Several modifications to the original method for the preparation of these dendritic fragments are detailed.

Synthesis and properties of a new class of polyether dendritic fragments: Useful building blocks for functional dendrimers

Polyether dendritic sectors 1-4 from the first to the fourth generations, respectively, were prepared by a convergent approach from readily available 4-tert-butylphenol, phloroglucinol and 1,3-dibromopropane. Using a three-step iterative synthetic sequence involving mono-O-alkylation of [Gn]-OH with excess 1,3-dibromopropane, bis-O-alkylation of the resulting compound with 5-benzyloxyresorcinol 5 followed by hydrogenolysis with palladium catalyst, [Gn(n + 1)]-OH of the next higher generation could be prepared in good yields. These dendritic sectors have good solubility properties and are inert in both acidic and basic media, and do not show any redox behaviour from-2.0 to +1.9 V. Hence they are useful dendritic building blocks for the preparation of functional dendrimers.