17623-99-3

Basic information

• Product Name: 1,4-Dihydroxyxanthone
• Synonyms: 1,4-Dihydroxyxanthone
• CAS NO: 17623-99-3
• Molecular Formula: C13H8O4
• Molecular Weight: 228.20022
• Mol File: 17623-99-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-Dihydroxyxanthone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dihydroxyxanthone(17623-99-3)
• EPA Substance Registry System: 1,4-Dihydroxyxanthone(17623-99-3)

Safety Data

• Hazardous Substances Data: 17623-99-3(Hazardous Substances Data)

Usage

Chemical class

Xanthone class of compounds

Physical appearance

Yellow, crystalline powder

Solubility

Soluble in hot water, alcohol, and alkalis

Melting point

238-240°C

Antioxidant properties

Exhibits antioxidant activity by scavenging free radicals and protecting cells from oxidative damage

Anticancer properties

Potential to inhibit the growth of cancer cells, making it a candidate for cancer treatment

Applications

Investigated for use in pharmaceuticals, cosmetics, and food additives

Versatility

Potential applications in various fields due to its beneficial properties

Upstream product

• 90-02-8 salicylaldehyde 
• 106-51-4 p-benzoquinone 
• 123-31-9 hydroquinone 
• 24396-24-5 2-(dimethoxymethyl)phenol 
• 3958-82-5 2-bromo-1,4-benzoquinone 
• 1352089-62-3 C₁₃H₈O₄ 
• 108-46-3 recorcinol 
• 69-72-7 salicylic acid 
• 110-86-1 pyridine 
• 719-41-5 1-hydroxy-9H-xanthen-9-one 
• 118-61-6 2-hydroxy-benzoic acid ethyl ester 

Relevant articles and documents

Construction of Highly Functionalized Xanthones via Rh-Catalyzed Cascade C-H Activation/ O-Annulation

A facile and efficient strategy for obtaining functionalized and multihydroxylated xanthones via Rh catalysis under redox-neutral conditions is developed. Diverse salicylaldehydes bearing heterocycles, aromatics, and fused aromatics can be rapidly coupled with 1,4-benzoquinones or 1,4-hydroquinones to afford valuable xanthones via cascade C-H/O-H functionalization and annulation. This protocol provides a rapid synthetic approach to obtain biologically active materials through late-stage functionalization and prepares natural products such as subelliptenone, pruniflorone N, and ravenelin.

An Abnormal Thermal Condensation of Hydroquinone with Ethyl Salicylate

Thermal condensation of hydroquinone with ethyl salicylate in refluxing diphenyl ether affords 1-hydroxyxanthone (I), 1,4-disalicyloxyhydroquinone (IIa), 4'-hyroxyphenyl salicylate (III), 1-hydroxy-4-salicyloxyxanthone (IVa), 1,4-dihydroxyxanthone (V) and 2-hydroxyxanthone (VI).The structures of these comnpounds have been confirmed by PMR and mass spectral data.