176249-70-0

Upstream product

• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 513-31-5 2-bromoallyl bromide 
• 87280-21-5 N-(2-bromo-2-propen-1-yl)-N-(2-propen-1-yl)amine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 82940-47-4 3,4-Dimethyl-1-(toluene-4-sulfonyl)-1H-pyrrole 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Relevant academic research and scientific papers

A palladium catalysed cyclisation-carbonylation of bromodienes: Control in carbonylation over facile β-hydride elimination

Conditions have been found for the efficient palladium mediated cyclisation-carbonylation of bromodienes to give γ,δ-unsaturated acids.

Convenient synthesis of heterobicycles by domino Heck-Diels-Alder reactions

Palladium(0)-catalyzed intramolecular cross coupling of bromodialkenylamines, bromoalkenylalkenamides and bromodialkenyl ethers followed by in situ [4+2] cycloaddition with suitable dienophiles gave tetrahydroisoindolines (31-73%yield), tetrahydroisoindolin-1-ones (43-51%) and hexahydrobenzo[c]furans (35-55%), and hexahydro-1H-[2]pyrindines (66-75%), respectively, each in one-pot operations.

Suppressed β-hydride elimination in palladium-catalyzed cascade cyclization-coupling reactions: An efficient synthesis of 3-arylmethylpyrrolidines

(formula presented) A novel type of palladium-catalyzed cascade cyclization-coupling reaction that proceeds with suppressed β-hydride elimination has been found. One of the N-sulfonyl oxygens is suggested to coordinatively stabilize an alkylpalladium inte