176316-83-9Relevant academic research and scientific papers
Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives
Bedeschi, Angelo,Zarini, Franco,Cabri, Walter,Candiani, Ilaria,Penco, Sergio,Capolongo, Laura,Ciomei, Marina,Farao, Mariella,Grandi, Maria
, p. 671 - 674 (1996)
A new family of water soluble camptothecin derivatives is described. Their synthesis, in vitro cytotoxicity, and in vivo antitumor activity is reported. Compounds 5a and 5c displayed excellent in vivo antitumor activity both ip and iv.
