176326-65-1

Upstream product

• 76-83-5 trityl chloride 
• 73616-27-0 5-amino-1-(2-hydroxyethyl)-1H-pyrazole 

Downstream Products

• 689178-24-3 1-[2-(4-nitrophenoxy)ethyl]-N-trityl-1H-pyrazol-5-amine 
• 689180-58-3 2-[5-(tritylamino)-1H-pyrazol-1-yl]ethyl 4-methylbenzenesulfonate 
• 689179-09-7 1-{2-[(5-nitro-2-pyridinyl)oxy]ethyl}-N-trityl-1H-pyrazol-5-amine 

Relevant academic research and scientific papers

AMIDE COMPOUNDS

A compound of the formula (I) wherein R1 is hydrogen, lower alkyl, lower alkenyl, halo(lower)alkyl, cyclo(lower)alkyl, lower alkoxy, lower alkylthio, acyl, optionally substituted aryl or NR3R4; R2 is hydrogen; or aryl or heteroaryl, each of which may be substituted; X is direct bond or bivalent residue derived from piperazine; Y is -(A1)n#191-(A2?)?m#191-, wherein n and m are independently 0 or 1); is bivalent residue derived from arene or heteroarene; and is bivalent residue derived from arene or heteroarene, or a salt thereof. The compound of the present invention and a salt thereof inhibit apolipoprotein B (Apo B) secretion and are useful as a medicament for prophylactic and treatment of diseases or conditions resulting from elevated circulating levels of Apo B.