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Dexamethasone 21-bromoacetate is a chemical compound derived from dexamethasone, a potent synthetic glucocorticoid used in medical treatments for various inflammatory and immune system disorders. The addition of the bromoacetic group at the 21st carbon position of the dexamethasone molecule allows for the formation of conjugates with other molecules, such as peptides or proteins, through a reaction between the bromoacetate group and amine groups present in the target molecule. This conjugation can be used to study the interactions of dexamethasone with specific proteins or to develop new drug delivery systems. The chemical structure of dexamethasone 21-bromoacetate is characterized by its steroidal backbone, with the bromoacetic group attached to the 21st carbon, making it a valuable tool in medicinal chemistry and drug development.

1764-73-4

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1764-73-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1764-73-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,6 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1764-73:
(6*1)+(5*7)+(4*6)+(3*4)+(2*7)+(1*3)=94
94 % 10 = 4
So 1764-73-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H30BrFO6/c1-13-8-17-16-5-4-14-9-15(27)6-7-21(14,2)23(16,26)18(28)10-22(17,3)24(13,31)19(29)12-32-20(30)11-25/h6-7,9,13,16-18,28,31H,4-5,8,10-12H2,1-3H3/t13-,16+,17+,18+,21+,22+,23?,24+/m1/s1

1764-73-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-[(8S,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2-bromoacetate

1.2 Other means of identification

Product number -
Other names Dexamethason-bromacetat

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1764-73-4 SDS

1764-73-4Downstream Products

1764-73-4Relevant academic research and scientific papers

Affinity-Labelling Corticoids I. Synthesis of 21-Chloroprogesterone, Deoxycorticosterone 21-(1-Imidazole) Carboxylate, 21-Deoxy-21-Chloro Dexamethasone, and Dexamethasone 21-Mesylate, 21-Bromoacetate, and 21-Iodoacetate

Dunkerton, Lois V.,Markland, Francis S.,Li, Ming P.

, p. 1 - 6 (1982)

The efficient and unambiguous preparation of several C-21 substituted affinity-labelling corticoids are described.Included is an improved procedure for the preparation of 21-chloroprogesterone and the first reported synthesis of deoxycorticosterone 21-(1-imidazole) carboxylate.Dexamethasone derivatives prepared include seperate and unambiguous synthesis of 21-deoxy-21-chlorodexamethasone and dexamethasone 21-mesylate, as well as the first reported synthesis of dexamethasone 21-bromoacetate and dexamethasone 21-iodoacetate.

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