176433-49-1

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Dichloronicotinaldehyde is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
2,5-Dichloronicotinaldehyde is used as a precursor in the production of pesticides, herbicides, and fungicides, playing a crucial role in the creation of effective agricultural chemicals to protect crops and enhance yields.
Given its toxic and irritant properties, 2,5-Dichloronicotinaldehyde is classified as a hazardous substance, necessitating careful handling and proper safety measures during its use in both industrial and agricultural applications.

InChI:InChI=1/C6H3Cl2NO/c7-5-1-4(3-10)6(8)9-2-5/h1-3H

Downstream Products

• 7659-46-3 4-chloro-trans-crotononitrile 
• 519172-46-4 5-Chloro-2-{2-[4-(4-Fluoro-Benzyl)-(2R,5S)-2,5-Dimethyl-Piperazin-1-Yl]-2-Oxo-Ethoxy}-Pyridine-3-Carbaldehyde 
• 558465-93-3 (2,5-dichloro-3-pyridinyl)methanol 
• 1386986-57-7 5-chloro-3-(methoxymethyl)picolinic acid 
• 1386986-06-6 5-chloro-3-methoxymethyl-pyridine-2-carbonitrile 
• 1386984-01-5 5-chloro-3-methoxymethyl-pyridine-2-carboxylic acid [3-((R)-5-amino-3-difluoromethyl-3,6-dihydro-2H-[1,4]oxazin-3-yl)-4-fluoro-phenyl]-amide 
• 1386985-56-3 ((R)-5-{5-[(5-chloro-3-methoxymethyl-pyridine-2-carbonyl)-amino]-2-fluoro-phenyl}-5-difluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-yl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Methods of using piperazine derivatives

The present invention relates to compounds of the formula I and the pharmaceutically acceptable forms thereof; wherein X, Y, a, b, c, d, R1, R2, R3, R4 and R5 are as defined herein. Moreover, the present invention is also directed at pharmaceutical compositions comprising a compound of the formula I and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed at methods of using the herein described compounds and compositions for treating or preventing a disorder or condition that can be treated or prevented by antagonizing the CCR1 receptor in a mammal.

Process for the preparation of 2-halogenopyridinealdehydes and novel 2-halogenopyridinealdehydes

The reaction of cyanoolefins, aminocarbonylolefins or hydroxyiminoolefins with a Vilsmeier reagent leads to 2-halogenopyridines which bear aldehyde groups in the 3 and/or 5 position. These pyridinealdehydes are valuable intermediates for the preparation of pharmaceuticals and crop protection agents.