176504-66-8Relevant articles and documents
Haloarenes in the Duff reaction under high pressures 2. Formylation and amidomethylation of haloarenes in trifluoroacetic acid
Sedishev, I. P.,Agafonov, N. E.,Kutin, A. A.,Zhulin, V. M.
, p. 2127 - 2130 (2007/10/03)
Reactions of haloarenes with urotropine in CF3COOH at elevated temperatures and high pressures give the corresponding aromatic aldehydes and/or N-(haloarylmethyl)trifluoroacetamides.The yields of the products and their ratio depend on electronic properties of substituents in the aromatic ring.The reaction carried out in a mixture of CF3COOH and (CF3CO)2O affords only amides. - Keywords: haloarenes; Duff reaction; high pressure; haloarenecarbaldehydes; N-(haloarylmethyl)trifluoroacetamides.