176548-77-9

Upstream product

• 105-53-3 diethyl malonate 
• 56041-57-7 2',3'-dichloroacetophenone 

Downstream Products

• 315228-81-0 1-[3-Chloro-2-(5-chloro-benzothiazol-2-ylsulfanyl)-5-nitro-phenyl]-ethanone 
• 315228-89-8 1-[3-Chloro-5-nitro-2-(5-trifluoromethyl-benzothiazol-2-ylsulfanyl)-phenyl]-ethanone 
• 315228-94-5 1-[3-Chloro-2-(5-methyl-benzothiazol-2-ylsulfanyl)-5-nitro-phenyl]-ethanone 
• 1422348-16-0 C₁₉H₁₂Cl₄N₂O₄S 

Relevant academic research and scientific papers

ANAGRELIDE DERIVATIVES (IMIDAZO [2, 1-B] QUINAZOLIN - 2 - ONES ) AS PDE III INHIBITORS USEFUL AS ANTITHROMBOTIC AGENTS

This invention relates to the discovery of 5-substituted analogues of the selective platelet lowering agent anagrelide, which are extremely potent inhibitors of phosphodiesterase III (PDE III). The compounds are potentially useful agents for the treatment

Therapeutic modulation of PPARgamma activity

Modulators of PPARγ activity are used in methods of treating and/or preventing conditions such as osteoporosis, Alzheimer's disease, psoriasis and acne, and cancer.

Compounds for the modulation of PPARgamma activity

Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.