176640-18-9Relevant academic research and scientific papers
Design and synthesis of bisubstrate analogues for 3-hydroxy-3-methyl-glutaryl coenzyme A reductase
Taillefumier,De Fornel,Chapleur
, p. 615 - 618 (1996)
The coupling of metalated pyridine derivatives with a chiral Weinreb amide derived from gluconolactone followed by stereoselective reduction of the resulting ketone are the key steps of the synthesis of bisubstrates analogues of the HMGCoA reduction by HMGR.
