17665-00-8

Basic information

• Product Name: L-Leu-D-Val-OH
• Synonyms: N-L-Leucyl-D-valine;L-Leu-D-Val-OH
• CAS NO: 17665-00-8
• Molecular Formula: C₁₁H₂₂N₂O₃
• Molecular Weight: 230.3
• Mol File: 17665-00-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Leu-D-Val-OH(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leu-D-Val-OH(17665-00-8)
• EPA Substance Registry System: L-Leu-D-Val-OH(17665-00-8)

Safety Data

• Hazardous Substances Data: 17665-00-8(Hazardous Substances Data)

Usage

General Description

L-Leu-D-Val-OH is a dipeptide consisting of the amino acids L-leucine and D-valine. L-leucine is an essential amino acid that is important for protein synthesis and muscle growth, while D-valine is a non-proteinogenic amino acid that can exhibit antiproliferative and neuroprotective properties. L-Leu-D-Val-OH is a synthetic compound that may have potential applications in the pharmaceutical and biotechnology industries, including in the development of new drugs and therapeutic agents. Its unique combination of amino acids and structural properties may offer opportunities for further research and exploration in the field of chemical biology and medicinal chemistry.

Upstream product

• 7801-70-9 Z-Leu-Val 
• 76863-45-1 (S)-benzyl (1-azido-4-methyl-1-oxopentan-2-yl)carbamate 
• 4070-48-8 L-Valine methyl ester 
• 3190-70-3 L-leucine N-carboxyanhydride 
• 16652-76-9 L-valine benzyl ester p-toluenesulfonate salt 
• 84111-39-7 L-leucyl-L-valine benzyl ester 
• 72-18-4 L-valine 
• 4703-53-1 N-benzyloxycarbonyl-L-leucine hydrazide 
• 17645-49-7 L-valine benzyl ester benzenesulfonate 

Downstream Products

• 1217336-50-9 C₄₉H₇₁N₇O₁₂S 

Relevant articles and documents

DPP4 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention provides a Dpp4 inhibitor which comprises a leucine derivative of the following formula (1) or a methionine derivative of the following formula (2): wherein each R1 and R3 represents a hydrogen atom (H) and an L-amino acid residue; R2 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline, alanine and phenylalanine) residue or L-amino-acid amide (except for proline amide, alanine amide and phenylalanine amide) residue; and R4 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline and alanine) residue or L-amino-acid amide (except for proline amide and alanine amide) residue. These derivatives also act as autophagy regulators.

Urethane-protected amino acid-N-carboxyanhydrides

The invention relates to urethane-protected amino acid-N-carboxyanhydride and N-thiocarboxyanhydride compounds which are useful in peptide, polypeptide and protein synthesis. Disclosed herein is the preparation and use of these novel compounds.