17665-69-9Relevant academic research and scientific papers
Palladium-Catalyzed Synthesis of β,β-Diaryl α,β-Unsaturated Ketones
Zheng, Yi-Lin,Xiao, Li,Xie, Qiong,Shao, Li-Ming
, p. 1455 - 1465 (2019)
We herein describe a versatile palladium-catalyzed synthesis of β,β-diaryl α,β-unsaturated ketones. A broad range of aryl halides react with β-arylbutanones to afford biologically useful, symmetrical and unsymmetrical ketones. The use of 4,5-diazafluoren-9-one and oxygen makes this one-pot reaction more applicable. A plausible mechanism involving palladium-catalyzed oxidative Heck-type cross-coupling is also proposed.
