176692-32-3Relevant academic research and scientific papers
Vanadium(II)- and Niobium(III)-Induced, Diastereoselective Pinacol Coupling of Peptide Aldehydes to Give a C2-Symmetrical HIV Protease Inhibitor
Kammermeier, Bernhard,Beck, Gerhard,Holla, Wolfgang,Jacobi, Detlev,Napierski, Bernd,Jendralla, Heiner
, p. 307 - 315 (2007/10/03)
Peptide aldehydes 15a-c are prepared without epimerization from enantiomerically pure (S)-α-amino acids (Scheme 3).Reductive pinacol homocoupling of 15a-c, induced by vanadium complex 11 or niobium complex 16 in refluxing THF, yields C2-symmetr
