176695-08-2Relevant academic research and scientific papers
Synthesis of 1-Alkyl-2,3-dihydro-2-(4-pyridinyl)-1H-isoindoles as Potential Selective Serotonin Reuptake Inhibitors
Kapples, Kevin J.,Shutske, Gregory M.
, p. 1335 - 1338 (1997)
Two 2,3-dihydro-2-(4-pyridinyl)-1H-isoindoles 2a,b have been synthesized by the reaction of isoindoline with 4-chloropyridines. In addition, a number of 1-alkyl-2,3-dibydro-2-(4-pyridinyl)-1H-isoindoles 2c-h were obtained from 2-(4-pyridinyl)phthalimide (
2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors
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, (2008/06/13)
2,3-dihydro-1H-isoindole derivatives of the formula STR1 where R1 -R5 and X are defined herein which are useful as serotonin reuptake inhibitors are disclosed. As such, these compounds may be useful for the treatment of depression, o
