176748-46-2

Upstream product

• 176748-29-1 [1-((2S,3S)-2-Hydroxymethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 68672-50-4 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(tert-butoxycarbonylmethoxyimino)acetic acid 
• 176748-31-5 [1-((2S,3S)-2-Methanesulfonyloxymethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 

Downstream Products

• 176748-47-3 [1-((2S,3S)-2-Mercaptomethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-49-5 [1-[(2S,3S)-2-(4-Nitro-phenoxycarbonylsulfanylmethyl)-4-oxo-azetidin-3-ylcarbamoyl]-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-51-9 [1-[(2S,3S)-2-(4-Nitro-phenoxycarbonylsulfanylmethyl)-4-oxo-1-sulfo-azetidin-3-ylcarbamoyl]-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of C-4 thio- and dithiocarbamate monobactam derivatives

New series of monobactam antibiotics, bearing thio- and dithiocarbamate derivatives as C-4 side chain, were synthesized. Some compounds were found to have good antibacterial activity against Gram-negative bacteria.