68672-50-4

Upstream product

• 54224-25-8 t-butyl (1,3-dioxo-1,3-dihydroisoindol-2-yloxy)acetate 
• 76-83-5 trityl chloride 
• 64987-08-2 ethyl 2-(2-aminothiazol-4-yl)glyoxylate 
• 68363-43-9 ethyl 2-oxo-2-(2-(tritylamino)thiazol-4-yl)acetate 
• 56834-02-7 tert-butyl aminooxyacetate 
• 68363-44-0 2-oxo-2-(2-(tritylamino)thiazol-4-yl)acetic acid 
• 5292-43-3 bromoacetic acid tert-butyl ester 

Downstream Products

• 75372-96-2 diphenylmethyl (6R,7R)-3-bromomethyl-7-[(Z)-2-(t-butoxycarbonylmethoxyimino)-2-(2-tritylaminothiazol-4-yl)acetamido]ceph-3-em-4-carboxylate 
• 128378-32-5 t-Butyl (6R,7R)-7-[2-(Z)-t-Butoxycarbonylmethoxyimino-2-(2-tritylaminothiazol-4-yl)acetamido]-3-cyclopropylceph-3-em-4-carboxylate 
• 176748-51-9 [1-[(2S,3S)-2-(4-Nitro-phenoxycarbonylsulfanylmethyl)-4-oxo-1-sulfo-azetidin-3-ylcarbamoyl]-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-49-5 [1-[(2S,3S)-2-(4-Nitro-phenoxycarbonylsulfanylmethyl)-4-oxo-azetidin-3-ylcarbamoyl]-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-31-5 [1-((2S,3S)-2-Methanesulfonyloxymethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-46-2 [1-((2S,3S)-2-Iodomethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-47-3 [1-((2S,3S)-2-Mercaptomethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 176748-29-1 [1-((2S,3S)-2-Hydroxymethyl-4-oxo-azetidin-3-ylcarbamoyl)-1-[2-(trityl-amino)-thiazol-4-yl]-meth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester 
• 68672-51-5 ester de tert-butylique de l'acide (acetoxy methyl)-3(<<<(dimethyl-1,1 ethoxy)-2 oxo-2 ethoxy>imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 

Relevant academic research and scientific papers

DEUTERATED O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA-LACTAMS

Provided herein are deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams, pharmaceutical compositions thereof and methods of treating infectious disease with deuterated compounds or pharmaceutical compositions thereof.

OXAMAZIN ANTIBIOTICS

Disclosed herein are oxamazin monobactam compounds and their use as antibiotics resistant to degradation by β-lactamases. Also disclosed are pharmaceutical compositions containing the compounds and methods of synthesis.

OXAMAZIN ANTIBIOTICS

Disclosed herein are oxamazin monobactam compounds and their use as antibiotics resistant to degradation by β-lactamases. Also disclosed are pharmaceutical compositions containing the compounds and methods of synthesis.