176774-98-4 Usage
Uses
Used in Pharmaceutical Industry:
Dihydro Artemisinin-d3 is used as a labeled metabolite for the development and study of antimalarial drugs. Its deuterium labeling allows for better understanding of the metabolic pathways and pharmacokinetics of Artemisinin and its derivatives, leading to improved drug design and optimization.
Used in Research and Development:
Dihydro Artemisinin-d3 is used as a research tool for studying the mechanism of action of antimalarial drugs, particularly in the context of drug resistance. Its deuterium labeling provides a unique signature that can be tracked and analyzed, helping researchers to better understand the interactions between the drug and its target.
Used in Quality Control and Standardization:
Dihydro Artemisinin-d3 is used as a reference material for quality control and standardization of Artemisinin and its derivatives in the pharmaceutical industry. Its deuterium labeling ensures accurate quantification and comparison of the active ingredients in various drug formulations, ensuring consistent quality and efficacy.
Used in Drug Metabolism and Pharmacokinetic Studies:
Dihydro Artemisinin-d3 is used as a stable isotope tracer in drug metabolism and pharmacokinetic studies. Its deuterium labeling allows for the tracking of the drug's distribution, metabolism, and excretion in the body, providing valuable insights into the drug's pharmacological properties and potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 176774-98-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,7,7 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 176774-98:
(8*1)+(7*7)+(6*6)+(5*7)+(4*7)+(3*4)+(2*9)+(1*8)=194
194 % 10 = 4
So 176774-98-4 is a valid CAS Registry Number.
176774-98-4Relevant academic research and scientific papers
Deuterated antimalarials: Synthesis of trideutero- artemisinin, dihydroartemisinin, and arteether
Avery, Mitchell A.,Bonk, Jason D.,Mehrotra, Sanjiv
, p. 249 - 254 (2007/10/03)
The stereoselective total synthesis of the antimalarial agents artemisinin-d3 (1), dihydroartemisinin-d3 (2), and arteether-d3 (3), incorporating 2H at C-16 (C-9 methyl) is reported.
