17683-36-2Relevant academic research and scientific papers
Synthesis of N-(dialkylaminoalkyl)alcohols by homogeneously catalyzed hydrogenolysis of cyclic N,O-acetals
Tararov, Vitali I.,Kadyrov, Renat,Riermeier, Thomas H.,B?rner, Armin
, p. 375 - 380 (2007/10/03)
The homogeneously catalyzed hydrogenation of 1,3-oxazolidines affording unsymmetrically substituted 2-N-(dialkylamino)ethanols is reported showing for the first time that Rh(I) catalysts based on chelating diphosphines can be advantageous for this reaction.
Reductive Cleavage of N-Substituted 2-Aryl-1,3-oxazolidines: Generation of α-Amino-Substituted Carbanions
Azzena, Ugo,Melloni, Giovanni,Nigra, Cristina
, p. 6707 - 6711 (2007/10/02)
The behavior of several N-substituted 2-aryl-1,3-oxazolidines has been investigated under conditions of electron transfer from alkali metals in aprotic solvents.The reduction led to the regioselective cleavage of the benzylic carbon-oxygen bond, with formation of the corresponding N-substituted benzylamino alcohols in good yields.Investigation of the mechanism of this reductive cleavage, with the aid of labeling experiments, showed the intermediate formation of α-tertiary amino-substituted carbanions.
DERIVATIVES OF OPTICALLY ACTIVE (1-PHENYLETHYL)AMINE IN COMPLEXES WITH LITHIUM ALUMINUM HYDRIDE FOR THE ASYMMETRIC REDUCTION OF A CARBONYL GROUP
Potapov, V. M.,Dem'yanovich, V. M.,Maleev, V. I.
, p. 1606 - 1609 (2007/10/02)
(R)-1-Phenylethanol is formed preferentially in the reduction of acetophenone by the complexes of lithium aluminum hydride with (-)-(2-hydroxyethyl)(1-phenylethyl)amine and (-)-methyl(2-hydroxyethyl)(1-phenylmethyl)amine.
