176850-50-3

Upstream product

• 53917-82-1 β-benzoylpropionyl chloride 
• 176850-44-5 4-Oxo-4-phenyl-butyric acid (2S,3R,3aS,6R,6aR)-2-benzyloxy-6-hydroxy-hexahydro-furo[3,2-b]furan-3-yl ester 

Downstream Products

• 111138-03-5 (R)-4-phenylbutyrolactone 
• 111138-02-4 (-)-(S)-5-phenyl-4,5-dihydrofuran-2(3H)-one 
• 34674-93-6 4-hydroxy-4-phenylbutanoic acid 

Relevant academic research and scientific papers

A facile synthesis of optically active lactones using benzyl-3,6-anhydro glucofuranoside as chiral auxiliary

A highly enantioselective synthesis of γ- and δ-lactones using an anhydrofuranoside derived from D-glucose as chiral auxiliary is described.

Asymmetric induction using novel chiral auxiliaries derived from D-glucose

Asymmetric synthesis of lactones 15a-16b, using the novel auxiliaries 1 and 2 readily available from D-glucose, is described.