176895-32-2

Upstream product

• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 100-58-3 phenylmagnesium bromide 
• 172025-43-3 (R)-1-[(4R,5S)-5-(Hydroxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-ethane-1,2-diol 

Downstream Products

• 172025-46-6 (S)-2-[((4S,5S)-5-Benzyl-2,2-dimethyl-[1,3]dioxolane-4-carbonyl)-amino]-4-methyl-pentanoic acid benzyl ester 
• 172025-48-8 (S)-2-((2S,3S)-2,3-Dihydroxy-4-phenyl-butyrylamino)-4-methyl-pentanoic acid benzyl ester 
• 58970-76-6 bestatin 
• 121445-53-2 N-<(2S,3S)-3-azido-2-hydroxy-4-phenylbutanoyl>-L-leucine benzyl ester 
• 172025-45-5 (4S,5S)-5-Benzyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid 

Relevant academic research and scientific papers

Synthesis of Bestatin, a Potent Inhibitor of Leukotriene A4 Hydrolase, by an N3 Nucleophile Reaction to a Non-protected Diol

The synthesis of bestatin (1), based on the regio-selective introduction of a nitrogen function to a non-protected diol 9, is described.

Application of an enyne metathesis/diels-alder cycloaddition sequence: A new versatile approach to the syntheses of C-Aryl glycosides and spiro- C-Aryl glycosides

An efficient approach for the synthesis of a variety of C-aryl and spiro- C-aryl glycosides is described. This diversity-oriented strategy employed here relies on a sequential enyne metathesis to generate the 1,3-diene moiety and Diels-Alder reaction with