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• 70-55-3 toluene-4-sulfonamide 
• 4231-26-9 diethylamino-1 phenyl-2 acetylene 
• 941-55-9 4-toluenesulfonyl azide 
• 121-44-8 triethylamine 
• 536-74-3 phenylacetylene 
• 884866-01-7 1-(4-methylbenzensulfonyl)-4-phenyl-1H-1,2,3-triazole 
• 109-89-7 diethylamine 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

One-pot multicomponent synthesis of N-sulfonyl amidines using magnetic separable nanoparticles-decorated N-heterocyclic carbene complex with copper

Magnetic separable nanoparticles-decorated N-heterocyclic carbene complex with copper (MNP[1-Methyl benzimidazole]NHC@Cu) has been prepared by covalent grafting of ionic liquid like 1-methyl benzimidazole unit on the surface of chlorofunctionalized Fesub

N-SULFONYL AMIDINE SYNTHESIS VIA THREE-COMPONENT COUPLING REACTION USING HETEROGENEOUS COPPER CATALYST

The present invention relates to a method of synthesizing N-sulfonyl amidine. More specifically, the present invention relates to the method of synthesizing N-sulfonyl amidine through a three-component coupling reaction using a heterogeneous copper catalyst; and optimization of reaction conditions applied thereto. The method is able to obtain corresponding N-sulfonyl amidine at high yield with respect to various substrates by performing a three-component coupling reaction of terminal alkyne, sulfonyl azide and amine by using a heterogeneous copper catalyst (Cu@C) obtained by pyrolyzing HKUST-1 which is a type of a metal-organic framework, and enables the heterogeneous copper catalyst to be reused at least four or more times without significant loss of catalytic activities since the heterogeneous copper catalyst has structural stability.COPYRIGHT KIPO 2018

Highly Efficient Synthesis of N -Sulfonylamidines via Silver-Catalyzed or Metal-Free Thermally Promoted Denitrogenative Amination of N -Sulfonyl-1,2,3-triazoles

A highly efficient synthesis of N-sulfonylamidines from N-sulfonyl-1,2,3-triazoles and amines is reported. This transformation undergoes silver-catalyzed or metal-free thermally promoted denitrogenation of N-sulfonyl-1,2,3-triazoles to afford N-sulfonylketenimine intermediates and subsequent nucleophilic addition with amines. The amine plays dual roles as base and nucleophile.

N-Sulfonyl amidine synthesis via three-component coupling reaction using heterogeneous copper catalyst derived from metal-organic frameworks

Three-component coupling reaction of terminal alkyne, sulfonyl azide, and amine for the synthesis of N-sulfonyl amidine was developed using heterogeneous Cu@C catalyst, which was generated by pyrolysis of HKUST-1 (Cu3(BTC)2, BTC?=?1,

Cu-catalyzed aerobic oxidative three-component coupling route to N -sulfonyl amidines via an ynamine intermediate

Cu-catalyzed aerobic oxidative three-component coupling of a terminal alkyne, secondary amine, and sulfonamide enables efficient synthesis of amidines. The use of Cu(OTf)2 (5 mol %) produces amidines selectively without Glaser-Hay alkyne homocoupling products. Preliminary studies suggest that the reaction pathway involves initial oxidative coupling of the terminal alkyne with the secondary amine, followed by hydroamidation of the ynamine intermediate with the sulfonamide.

Syntheses of N-sulfonyl-N,N-disubstituted amidines via a three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes

A facile and efficient synthesis of N-sulfonyl-N,N-disubstituted amidines has been achieved via a CuI-catalyzed three-component free-radical coupling reaction of tertiary amines and arenesulfonyl azides with terminal alkynes in the presence of azodiisobut

Formation of N-sulfonylamidines by copper-catalyzed coupling of sulfonyl azides, terminal alkynes, and trialkylamines

A copper-catalyzed synthesis of N-sulfonylamidines via three-component coupling of sulfonyl azides, terminal alkynes, and trialkylamines is reported.