176965-94-9

Upstream product

• 145644-82-2 (1R,2S,5R)-8-phenylmenthyl 2-acetamidoacrylate 
• 106-99-0 buta-1,3-diene 

Downstream Products

• 176965-96-1 (+)-(1'R,2'S,5'R)-8'-phenylmenthyl (1R,5S)-3-methyl-2-oxa-4-azabicyclo<3.3.1>non-3-ene-5-carboxylate 
• 176965-97-2 (+)-(1'R,2'S,5'R)-8'-phenylmenthyl (1S,3R)-1-amino-3-hydroxy-1-cyclohexanecarboxylate 
• 172299-73-9 (+)-(1S,3R)-1-amino-3-hydroxy-1-cyclohexanecarboxylic acid 
• 176965-95-0 (+)-(1'R,2'S,5'R)-8'-phenylmenthyl (1S,5S,8S)-3-methyl-exo-8-iodo-2-oxa-4-azabicyclo<3.3.1>non-3-ene-5-carboxylate 

Relevant academic research and scientific papers

Synthesis of a new enantiomerically pure constrained homoserine

The use of the Diels-Alder reaction between 1,3-butadiene and chiral 2-acetamidoacrylates as the key step followed by stereocontrolled transformations allows the synthesis of (1S,3R)-1-amino-3-hydroxycyclohexanecarboxylic acid, a new type of constrained h