176972-42-2Relevant academic research and scientific papers
Synthesis of 3-aryl- and 3-aryl-3,4-dihydroisocoumarins
Ahmad, Hafiz B.,Rama, Nasim H.,Hussain, Mazhar,Hussain, Muhammad T.,Qasim, Malik M.,Hameed, Shahid,Malana, Muhammad A.,Malik, Abdul
, p. 611 - 615 (2007/10/03)
The condensation of homophthalic acid 6 with the appropriate acid chlorides 7a-c yield the respective isocoumarins 8a-c, which are converted to keto-acids 9a-c by alkaline hydrolysis. The 3,4-dihydroisocoumarins 12a-c are obtained by reduction of the keto
