176980-36-2 Usage
Description
(3-Formyl-phenyl)-carbamic acid tert-butyl ester, also known as tert-butyl (3-formylphenyl)carbamate, is a carbamate ester with the molecular formula C12H15NO3. It is a white crystalline solid that is soluble in organic solvents and slightly soluble in water. This chemical compound is frequently used as a reagent in organic synthesis and pharmaceutical research, particularly as a protecting group for amines. Its versatile reactivity and stability make it a valuable building block for the synthesis of various pharmaceutical and agrochemical products.
Uses
Used in Organic Synthesis:
(3-Formyl-phenyl)-carbamic acid tert-butyl ester is used as a protecting group for amines in organic synthesis. It provides a stable and easily removable protection, allowing for the selective modification of amines in complex molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3-Formyl-phenyl)-carbamic acid tert-butyl ester is used as a building block for the synthesis of various pharmaceutical products. Its versatility and reactivity enable the development of new compounds with potential therapeutic applications.
Used in Agrochemical Synthesis:
(3-Formyl-phenyl)-carbamic acid tert-butyl ester is also utilized in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural chemicals.
Safety Precautions:
It is important to handle (3-Formyl-phenyl)-carbamic acid tert-butyl ester with care, as it is classified as harmful if swallowed and can cause irritation to the eyes and skin upon contact. Proper safety measures, such as wearing protective clothing and using appropriate containment, should be taken during its use in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 176980-36-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,9,8 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 176980-36:
(8*1)+(7*7)+(6*6)+(5*9)+(4*8)+(3*0)+(2*3)+(1*6)=182
182 % 10 = 2
So 176980-36-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO3/c1-12(2,3)16-11(15)13-10-6-4-5-9(7-10)8-14/h4-8H,1-3H3,(H,13,15)
176980-36-2Relevant articles and documents
CLPX INHIBITORY COMPOUNDS FOR THE TREATMENT OF MULTI RESISTANT STAPHYLOCOCCUS AUREUS VIRULENCE AND FOR THE TREATMENT OF LEUKEMIA
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Page/Page column 27, (2018/07/26)
The present invention relates to antibiotic compounds and their use as ClpX inhibitors and in the treatment of bacterial infections, such as infections with multi-resistant Staphylococcus aureas, and in the treatment of leukemia. The present invention fur
Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling of Secondary α-(Trifluoromethyl)benzyl Tosylates
Brambilla, Marta,Tredwell, Matthew
supporting information, p. 11981 - 11985 (2017/09/20)
A palladium-catalyzed C(sp3)?C(sp2) Suzuki–Miyaura cross-coupling of aryl boronic acids and α-(trifluoromethyl)benzyl tosylates is reported. A readily available, air-stable palladium catalyst was employed to access a wide range of functionalized 1,1-diaryl-2,2,2-trifluoroethanes. Enantioenriched α-(trifluoromethyl)benzyl tosylates were found to undergo cross-coupling to give the corresponding enantioenriched cross-coupled products with an overall inversion in configuration. The crucial role of the CF3 group in promoting this transformation is demonstrated by comparison with non-fluorinated derivatives.
A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus
Fetzer, Christian,Korotkov, Vadim S.,Th?nert, Robert,Lee, Kyu Myung,Neuenschwander, Martin,von Kries, Jens Peter,Medina, Eva,Sieber, Stephan A.
supporting information, p. 15746 - 15750 (2017/10/20)
The Staphylococcus aureus ClpXP protease is an important regulator of cell homeostasis and virulence. We utilized a high-throughput screen against the ClpXP complex and identified a specific inhibitor of the ClpX chaperone that disrupts its oligomeric sta
