177-12-8Relevant academic research and scientific papers
The mechanistic study and synthetic applications of the base treatment in the ozonolytic reactions
Hon, Yung-Son,Lin, Sheng-Wun,Lu, Ling,Chen, Yao-Jung
, p. 5019 - 5034 (2007/10/02)
The E1cb mechanism is the overwhelming process in the reaction of bases and ozonides. As a quenching agent in the ozonolysis of a variety of alkenes, the reactions involving triethylamine often gave better yields and proceeded faster than those involving methyl sulfide. On the other hand, in the presence of 4 A molecular sieves, the secondary amines reacted with mono- and 1,1-di-substituted ozonides to afford the reductive amination products in high yields. The formation of ammonium formate in the reaction mixture also supported the E1cb mechanism in the reaction of ozonide and amine.
The reactions of the ozonides with secondary amines: An efficient and novel way to prepare tertiary amine from mono- and 1,1-di-substituted alkenes via corresponding ozonides
Hon, Yung-Son,Lu, Ling
, p. 5309 - 5312 (2007/10/02)
The ozonolysis of mono- and 1,1-di-substituted olefins followed by treatment with secondary amines in the presence of 4A, molecular sieves to give the corresponding tertiary amine in high yields. This transformation involved four sequential reactions in the same flask.
