177019-79-3Relevant academic research and scientific papers
Synthesis of highly functionalized γ-lactam derivatives for use as conformational constraints in peptides
Martin-Martinez, Mercedes,Garcia-Lopez, Ma Teresa,Herranz, Rosario,Gonzalez-Muniz, Rosario
, p. 2471 - 2474 (2007/10/03)
A series of highly functionalized 2-oxopyrrolidine derivatives, as tripeptidemimetics in which the amino acid side chains are mounted on the γ-lactam template, were synthesized by nucleophilic opening of the δ-lactam system of the corresponding 3,6-dioxopyrrolo[1,2-a]pyrazine bicyclic analogues.
