177093-58-2 Usage
Uses
1. Used in Analytical Chemistry:
3-[4-(BROMOMETHYL)PHENYL]-7-(DIETHYLAMIN is used as a precolumn derivatization reagent for HPLC analysis of carboxylic acids. The application reason is its ability to enhance the detection and quantification of carboxylic acids in various samples, such as pharmaceuticals, environmental samples, and biological fluids.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-[4-(BROMOMETHYL)PHENYL]-7-(DIETHYLAMIN is used as a precolumn derivatization reagent for the analysis of drug substances and their metabolites. The application reason is its improved sensitivity and selectivity in detecting and quantifying carboxylic acid-containing compounds, which can be crucial for drug development and quality control processes.
3. Used in Environmental Analysis:
3-[4-(BROMOMETHYL)PHENYL]-7-(DIETHYLAMIN is employed as a precolumn derivatization reagent for the analysis of environmental samples, such as water, soil, and air. The application reason is its enhanced detection capabilities for carboxylic acid pollutants, which can help in monitoring and controlling environmental contamination.
4. Used in Biomedical Research:
In biomedical research, 3-[4-(BROMOMETHYL)PHENYL]-7-(DIETHYLAMIN is used as a precolumn derivatization reagent for the analysis of biological samples, such as blood, urine, and tissue extracts. The application reason is its ability to improve the detection and quantification of carboxylic acid-containing biomolecules, which can be essential for understanding various biological processes and disease mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 177093-58-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,0,9 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 177093-58:
(8*1)+(7*7)+(6*7)+(5*0)+(4*9)+(3*3)+(2*5)+(1*8)=162
162 % 10 = 2
So 177093-58-2 is a valid CAS Registry Number.
177093-58-2Relevant academic research and scientific papers
3-[4-(Bromomethyl)phenyl]-7-(diethylamino)-2H-1-benzopyran-2-one (MPAC-Br): A highly sensitive fluorescent derivatization reagent for carboxylic acids in high-performance liquid chromatography
Takechi, Haruko,Kamada, Seiji,Machida, Minoru
, p. 793 - 799 (2007/10/03)
7-Dimethylaminocoumarin derivatives were synthesized and the characteristics of their absorption and emission spectra were investigated. Among them, 3-aryl-7-dimethylaminocoumarins were shown to be promising candidates as the fluorogenic groups for highly sensitive derivatization reagents. Based on the spectroscopic studies, 3-[4-(bromomethyl)phenyl]-7-(diethylamino)-2H-1-benzopyran-2-one (MPAC-Br) was designed and synthesized as a fluorescent derivatization reagent for carboxylic acids in HPLC. Saturated carboxylic acids (C4-C18) were derivatized almost quantitatively into the corresponding fluorescent MPAC-esters by treatment with MPAC-Br. The MPAC-esters of these acids were clearly separated on a reversed-phase HPLC column (Inertsil ODS-2, mobile phase: methanol-water, excitation wavelength 403 nm; emission wavelength 474 nm). The detection limit (S/N=17) of lauric acid, as a test compound, was 15fmol/10μl.
