17716-46-0

Upstream product

• 108-24-7 acetic anhydride 
• 2835-58-7 2-aminoazobenzene 
• 60-35-5 acetamide 
• 55-21-0 benzamide 
• 1227476-15-4 Azobenzene 
• 858784-43-7 1,2-bis-(N'-phenyl-hydrazino)-benzene 

Downstream Products

• 34801-09-7 N-(2-aminophenyl)acetamide 
• 109596-26-1 N'-(2-methanesulfonyl-phenyl)-N-phenyl-diazene-N-oxide 

Relevant academic research and scientific papers

Cu(II)-catalyzed aerobic oxidative amidation of azoarenes with amides

A method for Cu(II)-catalyzed dehydrogenative amidation of azoarene using air as the terminal oxidant was developed. Various amides, such as arylamides, alkylamides, lactams, and imides, are all effective amidation reagents and provide the desired products in moderate to excellent yields. Notably, good yields can also be obtained on a gram-scale with this amidation reaction. In this protocol of azoarene amidation, the catalyst (Cu(OAc)2) and oxidant (air) are inexpensive and readily available, and the process is highly efficient and atom economical.

Preparation method of 2-aminoazo aromatic compound

The invention relates to a preparation method of 2-aminoazo aromatic compound. The 2-aminoazo aromatic compound is prepared by enabling an azo aromatic compound of a structure which is as shown in theformula I and amine to react; the reaction process comprises the following steps: directly adding the azo aromatic compound, the amine, a catalyst and a solvent into a reacting device, wherein the catalyst is copper acetate, the solvent is benzene, or dimethylbenzene and a mixture of the benzene or the dimethylbenzene, and the molar using amount of azobenzene is 1 to 3 times that of the amine; stirring and heating to the temperature of 100 to 130 DEG C, reacting for 24 hours, and separating a product to obtain the 2-aminoazo aromatic compound. The preparation method provided by the inventionis simple in synthesis route, low in raw material cost and high in yield.