17717-16-7

Basic information

• Product Name: 2,3,4,5-Tetrachloro-6-fluoropyridine
• Synonyms: 2,3,4,5-Tetrachloro-6-fluoropyridine;3,4,5,6-Tetrachloro-2-fluoropyridine
• CAS NO: 17717-16-7
• Molecular Formula: C₅Cl₄FN
• Molecular Weight: 234.87
• Mol File: 17717-16-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3,4,5-Tetrachloro-6-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4,5-Tetrachloro-6-fluoropyridine(17717-16-7)
• EPA Substance Registry System: 2,3,4,5-Tetrachloro-6-fluoropyridine(17717-16-7)

Safety Data

• Hazardous Substances Data: 17717-16-7(Hazardous Substances Data)

Usage

General Description

2,3,4,5-Tetrachloro-6-fluoropyridine, also known by its CAS number 370-50-5, is a chemical compound with the molecular formula C5HCl4FN. It is a colorless liquid that is used as an intermediate in the synthesis of various pharmaceutical products and agrochemicals. Due to its high level of chlorination, it is considered to be a highly toxic and hazardous substance, with potential harmful effects on the environment and human health. It is important to handle this chemical with extreme caution and follow proper safety protocols when working with it.

Upstream product

• 56-23-5 tetrachloromethane 
• 372-48-5 2-fluoropyridine 
• 2176-62-7 2,3,4,5,6-pentachloropyridine 
• 7664-39-3 hydrogen fluoride 
• 7789-23-3 potassium fluoride 
• 700-16-3 Pentafluoropyridine 

Downstream Products

• 17824-83-8 3,4,5,6-tetrachloropicolinonitrile 
• 1737-93-5 3,5-dichloro-2,4,6-trifluoropyridine 

Relevant articles and documents

Novel method for continuous production of fluroxypyr intermediate 3,5-dichloro-2,4,6-trifluoropyridine

The invention discloses a novel method for continuous production of fluroxypyr intermediate 3,5-dichloro-2,4,6-trifluoropyridine. The method comprises the steps as follows: N-stage reactors are used,compound pentachloropyridine and a catalyst are added to each stage of reactor, and hydrogen fluoride is introduced into the first-stage reactor after heating, melting and dehydration; unreacted hydrogen fluoride and produced hydrogen chloride tail gas in each stage of reactor are introduced into a condenser in each stage for condensing, the uncondensed tail gas is introduced into the next stage of reactor, the tail gas of the last stage of reactor is condensed by two condensers, hydrogen fluoride is separated, discharged, absorbed by a tail gas recovery device and used as by-product hydrochloric acid, and hydrogen fluoride condensed and recovered by the condenser in each stage is returned to each stage of reactor. With adoption of the synthesis method, hydrogen fluoride use rate is high,purity of by-product hydrochloric acid is high, and the content of hydrogen fluoride is lower than 1%; the method has the advantages of being high in product yield and reaction selectivity, solvent-free, low in production cost, simple in process, green and environmentally friendly, and is very suitable for industrial production.

POLYHALOAROMATIC EQUILIBRATIONS

Chromium oxide is a good catalyst for scrambling halogens among polyhaloaromatic compounds.Chloropentafluorobenzene and bromopentafluorobenzene disproportionate to hexafluorobenzene and the respective tetrafluorodihalobenzenes.Pentachloro- and pentafluoropyridines produce pyridines with intermediate numbers of both types of halogens.Cyano, trifluoromethyl and a single hydrogen can be present on the aromatic rings without interfering with the chemistry.