177178-57-3Relevant academic research and scientific papers
Spectroscopic Characterization and Biological Potential of Palladium(II) Complexes of Benzylidenehydrazinecarboxamide or -carbothioamide
Fahmi, Nighat,Saxena, Chitra,Singh, Ranvir V.
, p. 963 - 969 (2007/10/03)
In this article a brief account of the synthesis, stereochemistry, and biochemical behavior of palladium(II) complexes of benzylidenehydrazinecarboxamide or -carbothioamide is presented. The bimolar addition and substitution products have been characterized by elemental analyses, conductance measurements, molecular-weight determinations, magnetic susceptibilities, and spectral studies viz., IR, 1HNMR, 19FNMR, and UV. The data support the binding of sulfur or oxygen and nitrogen to the palladium in [Pd(RN-XH)2]Cl2 and [Pd(RN-X)2] (X is O or S) types of complexes. The square-planar geometry has been proposed. The representative free ligands (RN-XH) and their respective metal complexes were tested in vitro against a number of microorganisms to assess their antimicrobial properties and in vivo to test their sterilizing potential. The results are indeed positive.
