177202-64-1

Basic information

• Product Name: Formamide, N-[(2-aminophenyl)methyl]- (9CI)
• Synonyms: Formamide, N-[(2-aminophenyl)methyl]- (9CI)
• CAS NO: 177202-64-1
• Molecular Formula: C8H10N2O
• Molecular Weight: 150.1778
• Product Categories: AMINEPRIMARY
• Mol File: 177202-64-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 413.3±28.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• PKA: 15.54±0.23(Predicted)
• CAS DataBase Reference: Formamide, N-[(2-aminophenyl)methyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-[(2-aminophenyl)methyl]- (9CI)(177202-64-1)
• EPA Substance Registry System: Formamide, N-[(2-aminophenyl)methyl]- (9CI)(177202-64-1)

Safety Data

• Hazardous Substances Data: 177202-64-1(Hazardous Substances Data)

Upstream product

• 4252-31-7 N-formylbenzamide 
• 4403-69-4 2-amino-1-benzylamine 
• 1865-01-6 (4-nitrophenyl) formate 
• 1904-64-9 3,4-dihydroquinazoline 

Relevant articles and documents

Facile access to: N-formyl imide as an N-formylating agent for the direct synthesis of N-formamides, benzimidazoles and quinazolinones

N-Formamide synthesis using N-formyl imide with primary and secondary amines with catalytic amounts of p-toluenesulfonic acid monohydrate (TsOH·H2O) is described. This reaction is performed in water without the use of surfactants. Moreover, N-formyl imide is efficiently synthesized using acylamidines with TsOH·H2O in water. In addition, N-formyl imide was successfully used as a carbonyl source in the synthesis of benzimidazole and quinazolinone derivatives. Notable features of N-formylation of amines by using N-formyl imide include operational simplicity, oxidant- A nd metal-free conditions, structurally diverse products, and easy applicability to gram-scale operation.