177213-89-7

Upstream product

• 4965-33-7 2-methyl-7-chloroquinoline 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 177214-12-9 (S)-2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-hexanoic acid ethyl ester 
• 188699-83-4 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-hexanoic acid ethyl ester 
• 188699-87-8 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-dodecanoic acid ethyl ester 
• 188699-86-7 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-decanoic acid ethyl ester 
• 188699-85-6 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-octanoic acid ethyl ester 
• 188699-84-5 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-heptanoic acid ethyl ester 
• 188699-82-3 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-pentanoic acid ethyl ester 
• 188699-81-2 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-butyric acid ethyl ester 
• 188699-80-1 2-[2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-propionic acid ethyl ester 
• 188699-79-8 [2-({3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phenylamino}-methyl)-phenoxy]-acetic acid ethyl ester 
• 177213-91-1 E-2-{3-[2-(7-chloroquinolin-2-yl)ethenyl]phenylaminomethyl}phenol 
• 158546-57-7 (E)-3-(2-(7-chloroquinolin-2-yl)vinyl)aniline 

Relevant academic research and scientific papers

Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist

The present paper describes the structural modifications leading to the discovery of a new series of quinoline-containing cys-LT1 receptor (LTD4 receptor) antagonists. A structural optimization with respect to the in vitro receptor b