177217-34-4

Upstream product

• 100-52-7 benzaldehyde 
• 4299-70-1 L-tryptophan methyl ester 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 
• 7487-88-9 magnesium sulfate 

Downstream Products

• 139259-01-1 N-<(S)-2-carboxymethyl-2-(indol-3-yl)ethyl>-(6S)-2,3-didehydro-4-oxo-6-phenyl piperidine 
• 139259-07-7 N-<(S)-2-carboxymethyl-2-(indol-3-yl)ethyl>-(6R)-2,3-didehydro-4-oxo-6-phenyl piperidine 
• 177217-44-6 (6S)-N-[(S)-1-Carboxymethyl-2-(indol-3-yl)ethyl]-3-ethyl-4-oxo-6-phenyl-2,3-didehydropiperidine 
• 63229-68-5 methyl N-benzyl-L-tryptophanate 
• 50302-60-8 methyl 1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 
• 146609-57-6 1,2,3,4,6,7,12,12b-octahydro-2-oxoindolo<2,3-a>-(4R,6S,12bR)-6-carboxymethyl-4-phenyl quinolizine 
• 303744-26-5 2-benzyl-1-(2-iodo-phenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Catalytic asymmetric [3+2] cycloaddition of azomethine ylides. Development of a versatile stepwise, three-component reaction for diversity-oriented synthesis

We report a new catalyst system that should enhance the use of enantioselective 1,3-dipolar cycloadditions of azomethine ylides with electronic-deficient olefins in the divergent pathways of diversity-oriented synthesis (DOS). The underlying reaction is o

Sodium borohydride: A versatile reagent in the reductive N-monoalkylation of α-amino acids and α-amino methyl esters

α-Amino acids and α-amino methyl esters are easily converted to their N-monoalkyl derivatives by a reductive condensation reaction using several carbonyl compounds in the presence of sodium borohydride. This reducing agent has shown a wide versatility with minor but essential procedural variations. The reaction allows the α-monodeuterium labeling of the new N-substituent by use of sodium borodeuteride.

Process for the preparation of alpha-dimethylaminomethyl-tryptophan methyl ester

The invention is concerned with a process for the preparation of α-dimethylaminomethyltryptophan methyl ester, wherein (S)-2-benzylidene-amino)-3-(1H-indol-3-yl)-propionic acid methyl ester is reacted with 1-dimethylaminomethylbenzotriazole to give racemi

Pictet-Spengler/palladium catalyzed allenylation and carbonylation processes

The tactical combination of the Pictet-Spengler reaction with Pd catalyzed reactions with allene and with carbon monoxide provides rapid access to a range of tetrahydro-β-carboline and tetrahydroisoquinoline derivatives via intramolecular trapping of inte

Asymmetric synthesis of highly functionalized tetracyclic indole bases embodying the basic skeleton of yohimbine-and reserpine type alkaloids

Schiff bases derived from tryptophan methyl ester react with differently substituted electron-rich siloxy dienes in the presence of achiral or chiral boric acid esters to give enaminones 5 and 6 with high diastereomer ratios (up to >98:2). These intermedi

Asymmetric Synthesis of Indoloquinolizidin-2-ones Congeners to Yohimbine-Type Alkaloids

Schiff bases derived from tryptophan methyl ester and tryptamine react with Danishefkys diene in the presence of ZnCl2 to give enaminones which are subsequently transformed into indoloquinolizidin-2-ones by acid-catalyzed cyclization.These tetracyc