177315-34-3

Upstream product

• 152455-23-7 (S)-1-Benzyloxy-2,2-dimethyl-6,10-dithia-spiro[4.5]decane 
• 152455-21-5 Acetic acid (S)-2,2-dimethyl-6,10-dithia-spiro[4.5]dec-1-yl ester 
• 152455-25-9 (S)-2,2-Dimethyl-6,10-dithia-spiro[4.5]decan-1-ol 
• 92640-81-8 2,2-Dimethyl-6,10-dithiaspiro<4,5>decan-1-ol 
• 152455-13-5 1-methyl-2,5-cyclohexadiene-1-carboxaldehyde 
• 100-39-0 benzyl bromide 
• 59034-54-7 1-methyl-cyclohexa-2,5-dienecarboxylic acid methyl ester 
• 108-24-7 acetic anhydride 
• 177315-43-4 (2S,5R)-2-Benzyloxy-5-[(S)-hydroxy-(1-methyl-cyclohexa-2,5-dienyl)-methyl]-3,3-dimethyl-cyclopentanone 

Downstream Products

• 177315-40-1 Acetic acid (3S,3aR,3bS,7aR,8S,8aR)-3-benzyloxy-3a-hydroxy-2,2,7a-trimethyl-5-oxo-1,2,3,3a,3b,4,5,7a,8,8a-decahydro-cyclopenta[a]inden-8-yl ester 
• 177315-35-4 Acetic acid (S)-((1R,3S)-3-benzyloxy-4,4-dimethyl-2-oxo-cyclopentyl)-(1-methyl-4-oxo-cyclohexa-2,5-dienyl)-methyl ester 

Relevant academic research and scientific papers

A chemoenzymatic approach to the taxoid BC-substructure

The synthesis of a homochiral taxoid BC-unit containing the required functionalities on the B-ring periphery and a conveniently functionalized C-ring moiety by combination of enzymatic hydrolysis and the aldol-annelation-fragmentation sequence is describe