177410-67-2

Upstream product

• 108-24-7 acetic anhydride 
• 177410-73-0 (+/-)-5-chloro-α-(2,3-dimethoxyphenyl)-2-pivaloylaminobenzyl alcohol 
• 3282-30-2 pivaloyl chloride 
• 152911-54-1 (+/-)-2-amino-5-chloro-α-(2,3-dimethoxyphenyl)benzyl alcohol 

Downstream Products

• 177567-44-1 (E)-3-[{4-Chloro-2-[(S)-(2,3-dimethoxy-phenyl)-hydroxy-methyl]-phenyl}-(2,2-dimethyl-propyl)-carbamoyl]-acrylic acid ethyl ester 
• 177567-40-7 [(3R,5S)-7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(2,2-dimethyl-propyl)-2-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]oxazepin-3-yl]-acetic acid ethyl ester 
• 177410-77-4 (S)-[5-Chloro-2-(2,2-dimethyl-propylamino)-phenyl]-(2,3-dimethoxy-phenyl)-methanol 
• 171868-39-6 (3R,5S)-(-)-(3,5-trans)-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-1-neopentyl-2-oxo-4,1-benzoxazepine-3-acetic acid 
• 189059-58-3 (-)-2-amino-5-chloro-α-(2,3-dimethoxyphenyl)benzyl alcohol 
• 177410-76-3 (S)-(-)-5-chloro-α-(2,3-dimethoxyphenyl)-2-pivaloylaminobenzyl alcohol 

Relevant academic research and scientific papers

Microbial enantioselective ester hydrolysis for the preparation of optically active 4,1-benzoxazepine-3-acetic acid derivatives as squalene synthase inhibitors

Microbial enantioselective ester hydrolysis for the preparation of optically active (3R,5S)-(-)-5-phenyl-4,1-benzoxazepine-3-acetic acid derivatives as potent squalene synthase inhibitors was investigated. Pseudomonas diminuta and Pseudomonas taetrolens h