17746-77-9

Basic information

• Product Name: BENZOIC ACID,3-BROMO-2-HYDROXY-5-METHYL-,METHYL ESTER
• Synonyms: BENZOIC ACID,3-BROMO-2-HYDROXY-5-METHYL-,METHYL ESTER
• CAS NO: 17746-77-9
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.07
• Mol File: 17746-77-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BENZOIC ACID,3-BROMO-2-HYDROXY-5-METHYL-,METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOIC ACID,3-BROMO-2-HYDROXY-5-METHYL-,METHYL ESTER(17746-77-9)
• EPA Substance Registry System: BENZOIC ACID,3-BROMO-2-HYDROXY-5-METHYL-,METHYL ESTER(17746-77-9)

Safety Data

• Hazardous Substances Data: 17746-77-9(Hazardous Substances Data)

Upstream product

• 22717-57-3 methyl 6-hydroxy-m-toluate 
• 186581-53-3 diazomethane 
• 17746-75-7 3-bromo-5-methylsalicylic acid 

Downstream Products

• 1228005-48-8 (E)-1-(3-bromo-2-hydroxy-5-methylphenyl)-3-(2-chloro-6-ethoxyquinolin-3-yl)prop-2-en-1-one 
• 43135-49-5 2-bromo-6-(hydroxymethyl)-4-methyl-phenol 

Relevant articles and documents

WDR5 INHIBITORS AND MODULATORS

Described are imino-azacycle-benzamide compounds compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and c

Derivatives of 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene as PTP1B inhibitors with hypoglycemic activity

Disalicylic acid derivatives with stilbene and bis-styrylbenzene skeleton were synthesized as PTP1B inhibitors. The most potent in this series exhibited a submicromolar IC50 value. One of the compounds 7b was tested in an animal model for its efficacy as an anti-diabetic or an anti-obesity agent. In feeding compound 7b to diet-induced obese mice, no significant differences in weight gain and food consumption were observed between the drug-treated and the obese control mice. However, 7b significantly lowered the fasting glucose level and improved the glucose tolerance in the obesity-induced diabetic mice.