177763-08-5Relevant academic research and scientific papers
Palladium-Catalyzed Formal (5 + 2) Annulation between ortho-Alkenylanilides and Allenes
Cendón, Borja,Casanova, Noelia,Comanescu, Cezar C.,García-Fandi?o, Rebeca,Seoane, Andrés,Gulías, Moisés,Mascare?as, José L.
, p. 1674 - 1677 (2017)
2-Alkenyltriflylanilides react with allenes upon treatment with catalytic amounts of Pd(OAc)2 and Cu(II) to give highly valuable 2,3-dihydro-1H-benzo[b]azepines, in good yields, and with very high regio- and diastereoselectivities. Density functional theory (DFT) calculations suggest that the C-H activation of the alkenylanilide involves a classical concerted metalation-deprotonation (CMD) mechanism.
Heterogeneous Light-Mediated Reductive Dehalogenations and Cyclizations Utilizing Platinum Nanoparticles on Titania (PtNP@TiO2)
McTiernan, Christopher D.,Pitre, Spencer P.,Ismaili, Hossein,Scaiano, Juan C.
, p. 2819 - 2824 (2016/02/19)
The utility of platinum nanoparticles on titania (PtNP@TiO2) as a heterogeneous photoredox catalyst is evaluated using a series of reductive transformations. In comparison to TiO2 alone, TiO2 decorated with 0.2% PtNP shows enhanced efficiency, attributed to the NPs ability to both enhance light absorption and inhibit electron-hole pair recombination. Herein, we demonstrate that under an inert atmosphere and UVA/visible light irradiation a system consisting of our PtNP@TiO2 catalyst in conjunction with a sacrificial electron donor [diisopropylethylamine, (i-Pr)2NEt] can promote a variety of different reductive dehalogenations and cyclizations in moderate to excellent yields. In addition, the catalytic system is tolerant of many different functionalities and, due to its heterogeneous nature, holds the advantage of easy catalyst removal.
An intriguing effect of Yb(OTf)3-TMSCl in the halogenation of 1,1-disubstituted alkenes by NXS: Selective synthesis of allyl halides
Yamanaka, Masamichi,Arisawa, Mitsuhiro,Nishida, Atsushi,Nakagawa, Masako
, p. 2403 - 2406 (2007/10/03)
A novel protocol to effect the efficient selective halogenation of 1,1-disubstituted alkenes with NXS catalyzed by Yb(OTf)3-TMSCl, which affords the corresponding allyl halides in high yield, including allyl bromide, chloride, iodide and fluori
