1779-57-3Relevant academic research and scientific papers
An unexpected role of a trace amount of water in catalyzing proton transfer in phosphine-catalyzed (3 + 2) cycloaddition of allenoates and alkenes
Xia, Yuanzhi,Liang, Yong,Chen, Yuanyuan,Wang, Ming,Jiao, Lei,Huang, Feng,Liu, Song,Li, Yahong,Yu, Zhi-Xiang
, p. 3470 - 3471 (2007)
Through the joint forces of computation and experiment, the detailed mechanism of the Lu phosphine catalyzed (3 + 2) cycloaddition of allenoates and alkenes has been elucidated. The overall potential energy surface of the Lu (3 + 2) reaction has been computed. More importantly, theory and experiment have confirmed that a trace amount of water plays a critical role in assisting the process of [1,2] proton shift in the Lu reaction. Copyright
