177906-33-1

Basic information

• Product Name: [(S)-1-(5-{3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionylamino}-pentylcarbamoyl)-2-carbamoyl-ethyl]-carbamic acid tert-butyl ester
• Synonyms: [(S)-1-(5-{3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionylamino}-pentylcarbamoyl)-2-carbamoyl-ethyl]-carbamic acid tert-butyl ester
• CAS NO: 177906-33-1
• Molecular Weight: 604.707
• Mol File: 177906-33-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(S)-1-(5-{3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionylamino}-pentylcarbamoyl)-2-carbamoyl-ethyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-(5-{3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionylamino}-pentylcarbamoyl)-2-carbamoyl-ethyl]-carbamic acid tert-butyl ester(177906-33-1)
• EPA Substance Registry System: [(S)-1-(5-{3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionylamino}-pentylcarbamoyl)-2-carbamoyl-ethyl]-carbamic acid tert-butyl ester(177906-33-1)

Safety Data

• Hazardous Substances Data: 177906-33-1(Hazardous Substances Data)

Upstream product

• 177906-28-4 3-[Benzyloxycarbonyl-(3-methanesulfonyloxy-propyl)-amino]-propionic acid methyl ester 
• 177906-29-5 methyl 7-azido-4-benzyloxycarbonyl-4-azaheptanoate 
• 1476-39-7 1,5-diaminopentane dihydrochloride 
• 10494-79-8 methyl N-(3-hydroxypropyl)-β-alaninate 
• 177906-32-0 N-[N^α-(tert-butoxycarbonyl)-L-asparaginyl]-1,5-diaminopentane 
• 177906-31-9 3-[(3-Azido-propyl)-benzyloxycarbonyl-amino]-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester 

Downstream Products

• 1026030-33-0 (3-Azido-propyl)-[2-(5-{(S)-3-carbamoyl-2-[2-(3-hydroxy-phenyl)-acetylamino]-propionylamino}-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 1025828-13-0 (3-Azido-propyl)-(2-{5-[(S)-3-carbamoyl-2-(2-1H-indol-3-yl-acetylamino)-propionylamino]-pentylcarbamoyl}-ethyl)-carbamic acid benzyl ester 
• 177906-37-5 (3-Azido-propyl)-[2-(5-{(S)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 177906-36-4 (3-Azido-propyl)-[2-(5-{(S)-2-[2-(4-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 177906-34-2 {2-[5-((S)-2-Amino-3-carbamoyl-propionylamino)-pentylcarbamoyl]-ethyl}-(3-azido-propyl)-carbamic acid benzyl ester 

Relevant articles and documents

Syntheses and biological activities of joro spider toxin analogs to spidamine and joramine

In order to study the structure-activity relationships of spidamine and joramine found in the venom of Joro spider, Nephila clavata, we attempted to synthesize various analogs. Six analogs were convergently synthesized according to our previous method for the synthesis of spidamine, N-(3- aminopropyl-β-alanyl)-N'-(2,4-dihydroxyphenylacetyl-L-asparaginyl)-1,5- pentanediamine and joramine, N-(3-aminopropyl-β-alanyl)-N'-(4- hydroxyphenylacetyl-L-asparaginyl)-1,5-pentanediamine. The biological activities of the analogs and four intermediates were compared with those of synthetic spidamine and joramine in three bioassay systems, lobster neuromuscular synapse, cockroaches and mosquito larvae. The glutamate receptors in these systems were inhibited by some analogs, and the D- asparagine- or indoleacetyl-containing analogs were found to be strong inhibitors. These compounds have potential application as insecticides.