17792-11-9

Basic information

• Product Name: 3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one
• Synonyms: 3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one;6H-Dibenzo[b,d]pyran-6-one, 7,8,9,10-tetrahydro-3-hydroxy-4-(4-morpholinylmethyl)-
• CAS NO: 17792-11-9
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.3636
• Mol File: 17792-11-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 146-147 °C
• Boiling Point: 536°C at 760 mmHg
• Flash Point: 277.9°C
• Density: 1.34g/cm³
• Vapor Pressure: 4.22E-12mmHg at 25°C
• Refractive Index: 1.639
• PKA: 8.77±0.20(Predicted)
• CAS DataBase Reference: 3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(17792-11-9)
• EPA Substance Registry System: 3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one(17792-11-9)

Safety Data

• Hazardous Substances Data: 17792-11-9(Hazardous Substances Data)

Upstream product

• 5625-90-1 4-(morpholinomethyl)morpholine 
• 3722-44-9 3-hydroxy-7,8,9,10-tetrahydrobenzo[c]chromen-6-one 
• 108-46-3 recorcinol 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Relevant articles and documents

Modified coumarins. 7. Synthesis and biological activity of mannich bases of substituted 7,8,9,10-tetrahydrobenzo[c]chromen-6-ones

Condensation of 1- and 3-hydroxy-7,8,9,10-tetrahydrobenzo[c]chromen-6-ones with substituted 1,1-diaminomethanes produced Mannich bases containing a dialkylaminomethyl group in the 2- and 4-positions of 7, 8,9,10-tetrahydrobenzo[c]chromen-6-one. Pharmacological screening of 2-chloro-3-hydroxy-4-(1-pyrrolidinylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c] chromen-6-one in Wistar rats showed that it possesses low toxicity and acts as a stimulant of the central and peripheral nervous systems with indications of neuroleptic and tranquilizing activities.