177933-51-6

Basic information

• Product Name: (1S,2S)-2-Fluorocyclopropanecarboxylic Acid Ethyl Ester
• CAS NO: 177933-51-6
• Molecular Weight: 132.135
• Mol File: 177933-51-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2S)-2-Fluorocyclopropanecarboxylic Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-2-Fluorocyclopropanecarboxylic Acid Ethyl Ester(177933-51-6)
• EPA Substance Registry System: (1S,2S)-2-Fluorocyclopropanecarboxylic Acid Ethyl Ester(177933-51-6)

Safety Data

• Hazardous Substances Data: 177933-51-6(Hazardous Substances Data)

Upstream product

• 188428-48-0 cis-ethyl 2-fluorocyclopropanecarboxylate 

Downstream Products

• 155051-93-7 2-chloro-2-fluorocyclopropanecarboxylic acid ethyl ester 
• 127199-14-8 (1S,2S)-2-fluorocyclopropane-1-carboxylic acid 

Relevant articles and documents

Resolution of cis-2-fluorocyclopropanecarboxylic acid by a microbial enantioselective hydrolysis

The important key intermediate of quinolone analogue synthesis, (1S,2S)- 2-fluorocyclopropanecarboxylic acid, was prepared enantioselectively by a microbial resolution. One of the strains with the highest enzymatic specificity was selected from soil and when lyophilized cells were treated with corresponding ester, the remaining (1S,2S)-ester was obtained with high enantiomeric purity (98% e.e.).